Table 1.

Detection of CD11c+ and CD11c DC subsets in FL-treated individuals

Individual Day Percent of PBMCs Number of cells (×10−6/mL)
CD11c+CD11cCD11c+CD11c
FL  1  1.06 ± 0.2 0.83 ± 0.2  0.020 ± 0.007  0.016 ± 0.003 
 15  14.74 ± 3.7  3.10 ± 0.6  0.879 ± 0.325 0.185 ± 0.018  
Placebo  1  1.04 ± 0.2 0.75 ± 0.2  0.017 ± 0.007  0.012 ± 0.003 
 15  1.02 ± 0.3  0.82 ± 0.2  0.018 ± 0.009 0.014 ± 0.004 
Individual Day Percent of PBMCs Number of cells (×10−6/mL)
CD11c+CD11cCD11c+CD11c
FL  1  1.06 ± 0.2 0.83 ± 0.2  0.020 ± 0.007  0.016 ± 0.003 
 15  14.74 ± 3.7  3.10 ± 0.6  0.879 ± 0.325 0.185 ± 0.018  
Placebo  1  1.04 ± 0.2 0.75 ± 0.2  0.017 ± 0.007  0.012 ± 0.003 
 15  1.02 ± 0.3  0.82 ± 0.2  0.018 ± 0.009 0.014 ± 0.004 

PBMCs were isolated from the blood of FL-treated and placebo-treated individuals at days 1 and 15 and analyzed by flow cytometry for the proportion and total number of CD11c+IL-3R-α and CD11cIL-3R-α+ DCs per milliliter of blood. The data represent the mean ± SEM of 15 FL-treated and 5 placebo-treated individuals from all groups tested.

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