Detection of CD11c+ and CD11c− DC subsets in FL-treated individuals
Individual . | Day . | Percent of PBMCs . | Number of cells (×10−6/mL) . | ||
---|---|---|---|---|---|
CD11c+ . | CD11c− . | CD11c+ . | CD11c− . | ||
FL | 1 | 1.06 ± 0.2 | 0.83 ± 0.2 | 0.020 ± 0.007 | 0.016 ± 0.003 |
15 | 14.74 ± 3.7 | 3.10 ± 0.6 | 0.879 ± 0.325 | 0.185 ± 0.018 | |
Placebo | 1 | 1.04 ± 0.2 | 0.75 ± 0.2 | 0.017 ± 0.007 | 0.012 ± 0.003 |
15 | 1.02 ± 0.3 | 0.82 ± 0.2 | 0.018 ± 0.009 | 0.014 ± 0.004 |
Individual . | Day . | Percent of PBMCs . | Number of cells (×10−6/mL) . | ||
---|---|---|---|---|---|
CD11c+ . | CD11c− . | CD11c+ . | CD11c− . | ||
FL | 1 | 1.06 ± 0.2 | 0.83 ± 0.2 | 0.020 ± 0.007 | 0.016 ± 0.003 |
15 | 14.74 ± 3.7 | 3.10 ± 0.6 | 0.879 ± 0.325 | 0.185 ± 0.018 | |
Placebo | 1 | 1.04 ± 0.2 | 0.75 ± 0.2 | 0.017 ± 0.007 | 0.012 ± 0.003 |
15 | 1.02 ± 0.3 | 0.82 ± 0.2 | 0.018 ± 0.009 | 0.014 ± 0.004 |
PBMCs were isolated from the blood of FL-treated and placebo-treated individuals at days 1 and 15 and analyzed by flow cytometry for the proportion and total number of CD11c+IL-3R-α− and CD11c−IL-3R-α+ DCs per milliliter of blood. The data represent the mean ± SEM of 15 FL-treated and 5 placebo-treated individuals from all groups tested.