Comparison of the ITIMs of some of the members of the siglec family, PECAM-1 and biliary glycoprotein
| . | Proximal tyrosine . | Distal tyrosine . |
|---|---|---|
| CD33 | ELHYASL | TEYSEV |
| PECAM-1 | DVEYTEV | TVYSEI |
| Biliary glycoprotein | DVAYTVL | TVYSEV |
| CD22 | TVSYAIL | IHYSEL |
| Siglec-5 | ELHYASL | TEYSEI |
| MAG | AEYAEI | |
| SMP | PEYAEI |
| . | Proximal tyrosine . | Distal tyrosine . |
|---|---|---|
| CD33 | ELHYASL | TEYSEV |
| PECAM-1 | DVEYTEV | TVYSEI |
| Biliary glycoprotein | DVAYTVL | TVYSEV |
| CD22 | TVSYAIL | IHYSEL |
| Siglec-5 | ELHYASL | TEYSEI |
| MAG | AEYAEI | |
| SMP | PEYAEI |
ITIM indicates immunoreceptor tyrosine-based inhibitory motif; PECAM-1, platelet and endothelial cell adhesion molecule-1; siglec, sialic acid-binding, immunoglobulin-like lectins; MAG, myelin-associated glycoprotein; SMP, Schwann cell myelin protein.