Table 4. Erythropoietin and... | American Society of Hematology

Table 4.

Erythropoietin and erythropoiesis in patients with or without iron deficiency

Cohorts	Patients (n)	RBC removed (U)	Baseline RBC vol (mL)	RBC produced (mL)	Expansion (%)	Iron Rx	Reference
Endogenous erythropoietin
Iron deficient	6	3.8	1937	5.4 ± 2.8/kg	22	PO	32
Iron replete	28	3.4	1942	4.8 ± 2.3/kg	20	PO	32
Iron deficient	10	3.0	1503	367 ± 117	24	PO	27
Iron replete	77	3.0	1503	355 ± 157	23	PO	27
Erythropoietin therapy (3600 U/kg)^4-150
Iron deficient	13	4.9	1824	8.2 ± 3.0/kg	34	PO	32
Iron replete	23	5.1	1894	10.2 ± 4.0/kg	41	PO	32
Iron deficient	11	4.5	1535	540 ± 308	35	PO	27
Iron replete	75	4.5	1535	673 ± 190	44	PO	27

Cohorts	Patients (n)	RBC removed (U)	Baseline RBC vol (mL)	RBC produced (mL)	Expansion (%)	Iron Rx	Reference
Endogenous erythropoietin
Iron deficient	6	3.8	1937	5.4 ± 2.8/kg	22	PO	32
Iron replete	28	3.4	1942	4.8 ± 2.3/kg	20	PO	32
Iron deficient	10	3.0	1503	367 ± 117	24	PO	27
Iron replete	77	3.0	1503	355 ± 157	23	PO	27
Erythropoietin therapy (3600 U/kg)^4-150
Iron deficient	13	4.9	1824	8.2 ± 3.0/kg	34	PO	32
Iron replete	23	5.1	1894	10.2 ± 4.0/kg	41	PO	32
Iron deficient	11	4.5	1535	540 ± 308	35	PO	27
Iron replete	75	4.5	1535	673 ± 190	44	PO	27

Absent storage iron is defined as transferrin saturation <16% or ferritin <20 μg/L.

Total dose administered.