Endogenous erythropoietin-mediated erythropoiesis
| Patients (n) . | Blood removed (donated) . | Baseline RBC (mL) . | Blood produced . | Iron therapy . | Reference . | |||
|---|---|---|---|---|---|---|---|---|
| Requested/ donated (U) . | RBC (mL) . | RBC (mL) . | Expansion (%) . | |||||
| Standard phlebotomy | ||||||||
| 108 | 3 | 2.7 | 522 | 1884 | 351 | 19 | PO | 11 |
| 22 | 3 | 2.8 | 590 | 1936 | 220 | 11 | None | 12 |
| 45 | 3 | 2.9 | 621 | 1991 | 331 | 17 | PO | 12 |
| 41 | 3 | 2.9 | 603 | 1918 | 315 | 16 | PO + IV | 12 |
| Aggressive phlebotomy | ||||||||
| 30 | ≥3 | 3.0 | 540 | 2075 | 397 | 19 | None | 13 |
| 30 | ≥3 | 3.1 | 558 | 2024 | 473 | 23 | PO | 13 |
| 30 | ≥3 | 2.9 | 522 | 2057 | 436 | 21 | IV | 13 |
| 24 | 6 | 4.1 | 683 | 2157 | 568 | 26 | PO | 14, 15 |
| 23 | 6 | 4.6 | 757 | 2257 | 440 | 19 | PO | 16 |
| Patients (n) . | Blood removed (donated) . | Baseline RBC (mL) . | Blood produced . | Iron therapy . | Reference . | |||
|---|---|---|---|---|---|---|---|---|
| Requested/ donated (U) . | RBC (mL) . | RBC (mL) . | Expansion (%) . | |||||
| Standard phlebotomy | ||||||||
| 108 | 3 | 2.7 | 522 | 1884 | 351 | 19 | PO | 11 |
| 22 | 3 | 2.8 | 590 | 1936 | 220 | 11 | None | 12 |
| 45 | 3 | 2.9 | 621 | 1991 | 331 | 17 | PO | 12 |
| 41 | 3 | 2.9 | 603 | 1918 | 315 | 16 | PO + IV | 12 |
| Aggressive phlebotomy | ||||||||
| 30 | ≥3 | 3.0 | 540 | 2075 | 397 | 19 | None | 13 |
| 30 | ≥3 | 3.1 | 558 | 2024 | 473 | 23 | PO | 13 |
| 30 | ≥3 | 2.9 | 522 | 2057 | 436 | 21 | IV | 13 |
| 24 | 6 | 4.1 | 683 | 2157 | 568 | 26 | PO | 14, 15 |
| 23 | 6 | 4.6 | 757 | 2257 | 440 | 19 | PO | 16 |
Data are expressed as means.
PO, oral; IV, intravenous.