fVIII:c and fVIII:Ag of plasma fVIII with reduced binding to vWf
| Mutation . | fVIII:c* . | fVIII:Ag† . |
|---|---|---|
| Ile2098Ser (Le) | 4 | 5 |
| Ile2098Ser (Co) | 8 | ND |
| Ser2119Tyr (Zl) | 4 | <5 |
| Asn2129Ser (Ma) | 18 | 12 |
| Arg2150His (Ve) | 3 | ND |
| Arg2150His (LE) | 9 | ND |
| Arg2150His (LM) | 9 | 11 |
| Pro2153Gln (Or) | 2 | <5 |
| Mutation . | fVIII:c* . | fVIII:Ag† . |
|---|---|---|
| Ile2098Ser (Le) | 4 | 5 |
| Ile2098Ser (Co) | 8 | ND |
| Ser2119Tyr (Zl) | 4 | <5 |
| Asn2129Ser (Ma) | 18 | 12 |
| Arg2150His (Ve) | 3 | ND |
| Arg2150His (LE) | 9 | ND |
| Arg2150His (LM) | 9 | 11 |
| Pro2153Gln (Or) | 2 | <5 |
fVIII cofactor activity in patient plasma was measured in a coagulation assay. Results are expressed in percentage of the fVIII cofactor activity of a pool of normal plasma.
fVIII antigen measured in enzyme-linked immunosorbent assay. Results are expressed in percentage of the fVIII antigen level of a pool of normal plasma. ND indicates no data.