Table 1. Characteristics and mortality... | American Society of Hematology

Table 1.

Characteristics and mortality rates among 2950 males with hemophilia in six US states, 1993-1995

Characteristic	Total^*		Deaths		Mortality rate^†	Relative risk	95% CI
Characteristic	N	%	N	%	Mortality rate^†	Relative risk	95% CI
Age (years)
0-9	777	26	2	1	1.0	1.0
10-19	593	20	25	11	15.2	15.1	3.6-63.6
20-29	514	17	51	22	38.7	38.3	9.3-157
30-39	454	16	55	23	48.0	47.5	11.6-195
40-49	310	11	43	18	56.5	55.9	13.5-231
50-59	147	5	26	11	73.7	72.9	17.3-307
60-69	92	3	17	7	73.6	72.8	16.8-315
70+	63	2	17	7	118.9	117.6	27.2-509
Race/Ethnicity
White	2159	73	190	80	34.0	1.0
African-American	403	14	30	13	28.8	0.8	0.6-1.2
Hispanic	215	7	12	5	22.6	0.7	0.4-1.2
Other	119	4	3	1	9.8	0.3	0.1-0.9
Unknown	54	2	1	1	9.0	0.3	0.04-1.9
State of residence
New York	1214	41	110	47	35.2	1.0
Georgia	533	18	39	17	29.1	0.8	0.6-1.2
Massachusetts	423	14	30	12	29.3	0.8	0.6-1.2
Louisiana	294	10	24	10	29.6	0.8	0.5-1.3
Colorado	257	9	16	7	23.5	0.7	0.4-1.1
Oklahoma	229	8	17	7	28.4	0.8	0.5-1.3
Hemophilia type
A	2334	79	207	88	34.7	1.0
B	616	21	29	12	18.0	0.5	0.4-0.8
Disease severity
Mild	902	31	39	17	17.4	1.0
Moderate	717	24	41	17	21.7	1.2	0.8-1.9
Severe	1252	42	144	61	43.6	2.5	1.8-3.6
Insurance type
Private/HMO	1465	50	105	44	27.7	1.0
Medicare/Medicaid	923	31	108	46	45.8	1.6	1.3-2.2
Other/None	146	5	5	2	14.3	0.5	0.2-1.3
Hemophilia care source
Non-HTC	971	33	86	37	38.3	1.0
HTC	1979	67	149	63	28.1	0.7	0.6-0.9
Inhibitor
No	2810	95	226	96	31.4	1.0
Yes	140	5	10	4	26.0	0.8	0.4-1.6
Liver disease
No	2897	98	215	91	28.9	1.0
Yes	53	2	21	9	169.4	5.9	3.7-9.2
HIV serostatus
Negative	1366	46	25	11	6.8	1.0
Positive	781	26	186	78	94.7	14.0	9.2-21.2
Unknown^‡	803	28	25	11	13.2	1.9	1.1-3.4
AIDS
No	2731	93	109	46	15.2	1.0
Yes	219	7	127	54	300.9	19.7	15.3-25.5

Characteristic	Total^*		Deaths		Mortality rate^†	Relative risk	95% CI
Characteristic	N	%	N	%	Mortality rate^†	Relative risk	95% CI
Age (years)
0-9	777	26	2	1	1.0	1.0
10-19	593	20	25	11	15.2	15.1	3.6-63.6
20-29	514	17	51	22	38.7	38.3	9.3-157
30-39	454	16	55	23	48.0	47.5	11.6-195
40-49	310	11	43	18	56.5	55.9	13.5-231
50-59	147	5	26	11	73.7	72.9	17.3-307
60-69	92	3	17	7	73.6	72.8	16.8-315
70+	63	2	17	7	118.9	117.6	27.2-509
Race/Ethnicity
White	2159	73	190	80	34.0	1.0
African-American	403	14	30	13	28.8	0.8	0.6-1.2
Hispanic	215	7	12	5	22.6	0.7	0.4-1.2
Other	119	4	3	1	9.8	0.3	0.1-0.9
Unknown	54	2	1	1	9.0	0.3	0.04-1.9
State of residence
New York	1214	41	110	47	35.2	1.0
Georgia	533	18	39	17	29.1	0.8	0.6-1.2
Massachusetts	423	14	30	12	29.3	0.8	0.6-1.2
Louisiana	294	10	24	10	29.6	0.8	0.5-1.3
Colorado	257	9	16	7	23.5	0.7	0.4-1.1
Oklahoma	229	8	17	7	28.4	0.8	0.5-1.3
Hemophilia type
A	2334	79	207	88	34.7	1.0
B	616	21	29	12	18.0	0.5	0.4-0.8
Disease severity
Mild	902	31	39	17	17.4	1.0
Moderate	717	24	41	17	21.7	1.2	0.8-1.9
Severe	1252	42	144	61	43.6	2.5	1.8-3.6
Insurance type
Private/HMO	1465	50	105	44	27.7	1.0
Medicare/Medicaid	923	31	108	46	45.8	1.6	1.3-2.2
Other/None	146	5	5	2	14.3	0.5	0.2-1.3
Hemophilia care source
Non-HTC	971	33	86	37	38.3	1.0
HTC	1979	67	149	63	28.1	0.7	0.6-0.9
Inhibitor
No	2810	95	226	96	31.4	1.0
Yes	140	5	10	4	26.0	0.8	0.4-1.6
Liver disease
No	2897	98	215	91	28.9	1.0
Yes	53	2	21	9	169.4	5.9	3.7-9.2
HIV serostatus
Negative	1366	46	25	11	6.8	1.0
Positive	781	26	186	78	94.7	14.0	9.2-21.2
Unknown^‡	803	28	25	11	13.2	1.9	1.1-3.4
AIDS
No	2731	93	109	46	15.2	1.0
Yes	219	7	127	54	300.9	19.7	15.3-25.5

CI indicates confidence interval; HMO, health maintenance organization; HTC, hemophilia treatment center.

Total does not always equal 100% because of missing data.

Mortality rate in deaths per 1000 person years.

Includes untested individuals.