Comparison of HBV virological factors of recipients and donors for HBV-related hepatitis in group 1 patients
. | Patients with HBV-related hepatitis (n = 8) . | Patients without HBV-related hepatitis (n = 10) . | Incidence of HBV-related hepatitis . |
---|---|---|---|
Recipients' HBV virological characteristics | |||
HBsAg positive | 5 | 4 | 5/9 (55.6%) |
HBeAg positive | 1 | 1 | 1/2 (50%) |
HBV DNA positive by bDNA assay | 2 | 2 | 2/4 (50%) |
HBV DNA positive by PCR | 4 | 4 | 4/8 (50%) |
HBsAb positive, median titer in mIU/mL (range) | 1 (1200) | 5 (1400, 100-2800) | 1/6 (16.7%) |
Precore A1896 variant alone present | 0 | 2 | 0/2 (0%) |
Core promoter T1762/A1764variants alone present | 0 | 1 | 0/1 (0%) |
Both A1764 and A1896 + T1762 variants present | 2 | 0 | 2/2 (100%) |
A1764 and/or A1896 + T1762variants present | 2 | 3 | 2/5 (40%) |
Donors' HBV virological characteristics | |||
HBeAg positive | 1 | 4 | 1/5 (20%) |
HBV DNA present (by bDNA assay) | 54-150 | 14-150 | 5/6 (83.3%) |
HBV DNA present (by PCR) | 8 | 4 | 8/12 (66.7%) |
Precore A1896 variant alone present | 2 | 0 | 2/2 (100%) |
Core promoter T1762/A1764 variant alone present | 1 | 0 | 1/1 (100%) |
Both A1764 and A1896 + T1762 variants present | 2 | 0 | 2/2 (100%) |
A1764 and/or A1896 + T1762variants present | 54-150 | 0 | 5/5 (100%) |
. | Patients with HBV-related hepatitis (n = 8) . | Patients without HBV-related hepatitis (n = 10) . | Incidence of HBV-related hepatitis . |
---|---|---|---|
Recipients' HBV virological characteristics | |||
HBsAg positive | 5 | 4 | 5/9 (55.6%) |
HBeAg positive | 1 | 1 | 1/2 (50%) |
HBV DNA positive by bDNA assay | 2 | 2 | 2/4 (50%) |
HBV DNA positive by PCR | 4 | 4 | 4/8 (50%) |
HBsAb positive, median titer in mIU/mL (range) | 1 (1200) | 5 (1400, 100-2800) | 1/6 (16.7%) |
Precore A1896 variant alone present | 0 | 2 | 0/2 (0%) |
Core promoter T1762/A1764variants alone present | 0 | 1 | 0/1 (0%) |
Both A1764 and A1896 + T1762 variants present | 2 | 0 | 2/2 (100%) |
A1764 and/or A1896 + T1762variants present | 2 | 3 | 2/5 (40%) |
Donors' HBV virological characteristics | |||
HBeAg positive | 1 | 4 | 1/5 (20%) |
HBV DNA present (by bDNA assay) | 54-150 | 14-150 | 5/6 (83.3%) |
HBV DNA present (by PCR) | 8 | 4 | 8/12 (66.7%) |
Precore A1896 variant alone present | 2 | 0 | 2/2 (100%) |
Core promoter T1762/A1764 variant alone present | 1 | 0 | 1/1 (100%) |
Both A1764 and A1896 + T1762 variants present | 2 | 0 | 2/2 (100%) |
A1764 and/or A1896 + T1762variants present | 54-150 | 0 | 5/5 (100%) |
See the footnote to Table 1 for explanations of the abbreviations used.
P value of the difference <.05.