Characteristics of 99 adults infected with HIV-1 at baseline and at 1 year under HAART
| Patient no. . | Sex . | Preuse of antiviral drugs . | HAART regimen . | CD4+ T-cell count (cells/μL) . | Plasma viral load (log10 eq copies/mL) . | |||
|---|---|---|---|---|---|---|---|---|
| Initial . | Modification (mos)* . | Initial . | 1 y . | Initial . | 1 y . | |||
| I. Virologic responders† | ||||||||
| 1 | M | ddC/3TC | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (6) | 0 | 133 | 5.01 | < 1.7 |
| 2 | M | No | 3TC/d4T/IDV | No | 6 | 143 | 5.22 | < 1.7 |
| 3 | M | ZDV/3TC | 3TC/d4T/IDV | No | 7 | 217 | 4.63 | < 1.7 |
| 4 | M | ZDV/3TC | 3TC/d4T/IDV | No | 8 | 358 | 5.24 | 2.92 |
| 5 | M | ddC | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (6) | 10 | 200 | 4.48 | 1.74 |
| 6 | M | ddI/ddC | 3TC/d4T/IDV | No | 10 | 63 | 5.11 | 2.50 |
| 7 | F | ZDV/ddC | 3TC/d4T/IDV | No | 24 | 88 | 4.29 | < 1.7 |
| 8 | M | No | 3TC/d4T/IDV | No | 25 | 97 | 4.92 | < 1.7 |
| 9 | M | No | 3TC/d4T/IDV | No | 42 | 282 | 5.12 | 2.11 |
| 10 | M | ZDV/ddC | 3TC/d4T/IDV | No | 53 | 228 | 4.15 | < 1.7 |
| 11 | M | No | 3TC/d4T/IDV | No | 59 | 195 | 4.04 | < 1.7 |
| 12 | M | ZDV/ddC | 3TC/d4T/IDV | ZDV/3TC/IDV (6) | 60 | 253 | 4.27 | 2.11 |
| 13 | M | No | 3TC/d4T/IDV | No | 66 | 256 | 4.88 | < 1.7 |
| 14 | M | ZDV/3TC | 3TC/d4T/IDV | No | 67 | 197 | 4.09 | < 1.7 |
| 15 | M | ddI/3TC | 3TC/d4T/IDV | No | 70 | 149 | 4.27 | < 1.7 |
| 16 | F | ZDV/3TC | 3TC/d4T/IDV | No | 73 | 125 | 4.10 | < 1.7 |
| 17 | M | ddI/ddC | 3TC/d4T/IDV | No | 76 | 107 | 4.00 | < 1.7 |
| 18 | M | ZDV/3TC | 3TC/d4T/IDV | No | 82 | 207 | 4.75 | < 1.7 |
| 19 | F | ddI/ddC | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (6) | 84 | 218 | 4.36 | 2.29 |
| 20 | M | ZDV/3TC | 3TC/d4T/IDV | No | 100 | 342 | 4.76 | < 1.7 |
| 21 | M | No | 3TC/d4T/IDV | No | 114 | 290 | 5.19 | < 1.7 |
| 22 | M | 3TC/d4T | 3TC/d4T/IDV | No | 115 | 246 | 4.21 | < 1.7 |
| 23 | M | No | 3TC/d4T/IDV | No | 124 | 332 | 5.54 | < 1.7 |
| 24 | M | ddI/ddC | 3TC/d4T/IDV | No | 125 | 292 | 4.37 | < 1.7 |
| 25 | M | No | 3TC/d4T/IDV | No | 126 | 395 | 5.12 | < 1.7 |
| 26 | F | ddC | 3TC/d4T/IDV | No | 126 | 239 | 4.23 | < 1.7 |
| 27 | M | ZDV/ddI | 3TC/d4T/IDV | No | 129 | 285 | 4.41 | 2.23 |
| 28 | M | ZDV/ddI | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (6) | 141 | 101 | 4.25 | < 1.7 |
| 29 | F | No | 3TC/d4T/IDV | No | 150 | 564 | 5.85 | 1.7 |
| 30 | M | ZDV/ddI | 3TC/d4T/IDV | No | 167 | 247 | 4.60 | < 1.7 |
| 31 | M | No | 3TC/d4T/IDV | No | 168 | 222 | 4.17 | < 1.7 |
| 32 | M | ZDV/ddC | 3TC/d4T/IDV | No | 172 | 199 | 5.05 | < 1.7 |
| 33 | F | No | 3TC/d4T/IDV | No | 174 | 512 | 5.10 | < 1.7 |
| 34 | F | No | 3TC/d4T/IDV | No | 177 | 188 | 5.33 | < 1.7 |
| 35 | F | ddI/ddC | 3TC/d4T/IDV | ZDV/3TC/IDV (1) | 180 | 357 | 4.79 | < 1.7 |
| 36 | M | ZDV/ddI | 3TC/d4T/IDV | No | 182 | 387 | 4.11 | < 1.7 |
| 37 | F | No | 3TC/d4T/IDV | No | 194 | 396 | 4.52 | < 1.7 |
| 38 | M | ddI/ddC | 3TC/d4T/IDV | No | 212 | 417 | 4.79 | < 1.7 |
| 39 | M | ZDV/ddI | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (5) | 215 | 300 | 4.05 | 2.79 |
| 40 | M | No | 3TC/d4T/IDV | No | 219 | 366 | 4.41 | 2.42 |
| 41 | M | No | 3TC/d4T/IDV | No | 253 | 307 | 5.18 | < 1.7 |
| 42 | M | ddC/3TC | 3TC/d4T/IDV | No | 253 | 534 | 4.45 | < 1.7 |
| 43 | M | ZDV/ddC | 3TC/d4T/IDV | No | 259 | 381 | 4.15 | < 1.7 |
| 44 | M | No | 3TC/d4T/IDV | No | 259 | 358 | 4.55 | < 1.7 |
| 45 | M | ZDV/ddi | 3TC/d4T/IDV | ZDV/3TC/IDV (5) | 262 | 487 | 4.10 | < 1.7 |
| 46 | M | ddI/ddC | 3TC/d4T/IDV | No | 265 | 498 | 4.16 | < 1.7 |
| 47 | M | ddC | 3TC/d4T/IDV | No | 272 | 327 | 4.09 | 1.7 |
| 48 | M | ZDV/3TC | 3TC/d4T/IDV | No | 274 | 587 | 4.40 | < 1.7 |
| 49 | M | No | 3TC/d4T/IDV | No | 280 | 422 | 4.70 | < 1.7 |
| 50 | M | No | 3TC/d4T/IDV | No | 291 | 725 | 4.33 | < 1.7 |
| 51 | M | No | 3TC/d4T/IDV | No | 312 | 360 | 4.00 | < 1.7 |
| 52 | M | No | 3TC/d4T/IDV | No | 321 | 452 | 4.23 | 2.70 |
| 53 | M | No | 3TC/d4T/IDV | No | 339 | 471 | 5.09 | < 1.7 |
| 54 | M | ZDV/ddI | 3TC/d4T/IDV | No | 343 | 642 | 5.43 | < 1.7 |
| 55 | M | No | 3TC/d4T/IDV | No | 345 | 605 | 4.67 | < 1.7 |
| 56 | M | No | 3TC/d4T/IDV | No | 363 | 730 | 4.25 | 2.12 |
| 57 | M | ZDV/ddC | 3TC/d4T/IDV | No | 386 | 672 | 4.26 | < 1.7 |
| 58 | M | No | 3TC/d4T/IDV | No | 512 | 938 | 4.17 | < 1.7 |
| 59 | F | ddI/ddC | 3TC/d4T/IDV | No | 683 | 828 | 4.16 | < 1.7 |
| II. Virologic transient responders‡ | ||||||||
| 60 | M | ZDV/ddC | 3TC/d4T/IDV | ZDV/3TC/IDV (6) | 4 | 119 | 4.23 | 3.11 |
| 61 | F | ZDV/ddC | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (6) | 6 | 176 | 4.14 | 4.33 |
| 62 | M | ZDV/3TC | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (6) | 10 | 95 | 4.61 | 3.74 |
| 63 | M | No | 3TC/d4T/IDV | No | 17 | 378 | 5.05 | 3.70 |
| 64 | M | ZDV/ddC | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (8) | 61 | 291 | 4.38 | 4.53 |
| 65 | M | ddC/d4T | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (8) | 65 | 224 | 4.44 | 4.11 |
| 66 | M | ZDV/ddC | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (7) | 78 | 155 | 4.81 | 3.12 |
| 67 | M | No | 3TC/d4T/IDV | No | 88 | 365 | 5.00 | 4.54 |
| 68 | F | ddI/ddC | 3TC/d4T/IDV | No | 105 | 175 | 5.49 | 3.11 |
| 69 | F | ddC/d4T | 3TC/d4T/IDV | No | 109 | 176 | 4.24 | 3.53 |
| 70 | M | ddI/ddC | 3TC/d4T/IDV | No | 114 | 324 | 4.99 | 3.81 |
| 71 | M | No | 3TC/d4T/IDV | No | 115 | 266 | 4.38 | 4.21 |
| 72 | M | ZDV | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (5) | 117 | 185 | 4.71 | 4.40 |
| 73 | M | No | 3TC/d4T/IDV | No | 146 | 251 | 4.09 | 3.00 |
| 74 | M | No | 3TC/d4T/IDV | No | 203 | 223 | 4.05 | 4.81 |
| 75 | F | ddI/ddC | 3TC/d4T/IDV | No | 244 | 307 | 4.95 | 5.11 |
| 76 | M | ZDV/ddI | 3TC/d4T/IDV | No | 257 | 464 | 4.82 | 4.11 |
| 77 | M | No | 3TC/d4T/IDV | No | 279 | 548 | 5.07 | 3.23 |
| 78 | M | No | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (6) | 286 | 453 | 5.27 | 3.22 |
| 79 | M | No | 3TC/d4T/IDV | No | 292 | 452 | 5.08 | 3.15 |
| 80 | M | ZDV/ddC | 3TC/d4T/IDV | No | 294 | 372 | 4.10 | 3.70 |
| 81 | M | ZDV/ddC | 3TC/d4T/IDV | No | 324 | 454 | 4.30 | 3.60 |
| 82 | M | No | 3TC/d4T/IDV | No | 571 | 506 | 4.61 | 5.70 |
| III. Virologic non responders1-153 | ||||||||
| 83 | M | ZDV/ddI | 3TC/d4T/IDV | No | 0 | 45 | 5.01 | 4.11 |
| 84 | M | ZDV/ddC | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (7) | 2 | 27 | 4.90 | 4.52 |
| 85 | M | ZDV/ddC | 3TC/d4T/IDV | No | 2 | 17 | 5.56 | 5.01 |
| 86 | M | ZDV/ddC | 3TC/d4T/IDV | No | 15 | 102 | 4.93 | 4.75 |
| 87 | M | ZDV/3TC | 3TC/d4T/IDV | No | 30 | 283 | 4.10 | 4.22 |
| 88 | M | ZDV/ddC | 3TC/d4T/IDV | ZDV/3TC/IDV (4) | 36 | 163 | 4.99 | 5.04 |
| 89 | M | ZDV/ddI | 3TC/d4T/IDV | No | 43 | 136 | 5.22 | 4.36 |
| 90 | M | ZDV/ddC | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (6) | 81 | 237 | 4.24 | 4.51 |
| 91 | M | ZDV/ddI | 3TC/d4T/IDV | No | 132 | 554 | 4.34 | 5.90 |
| 92 | M | 3TC/d4T | 3TC/d4T/IDV | No | 154 | 141 | 4.21 | 4.61 |
| 93 | M | ZDV/3TC | 3TC/d4T/IDV | No | 155 | 274 | 4.79 | 4.72 |
| 94 | F | 3TC | 3TC/d4T/IDV | No | 187 | 165 | 4.75 | 4.63 |
| 95 | M | ddI/ddC | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (8) | 194 | 277 | 4.19 | 5.03 |
| 96 | F | ZDV/ddI | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (7) | 213 | 329 | 4.47 | 4.10 |
| 97 | M | No | 3TC/d4T/IDV | ZDV/3TC/IDV (5) | 286 | 647 | 4.31 | 4.11 |
| 98 | M | ZDV/ddC | 3TC/d4T/IDV | ZDV/3TC/IDV (4) | 361 | 629 | 4.42 | 4.31 |
| 99 | M | ddI/ddC | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (8) | 430 | 539 | 5.13 | 4.67 |
| Patient no. . | Sex . | Preuse of antiviral drugs . | HAART regimen . | CD4+ T-cell count (cells/μL) . | Plasma viral load (log10 eq copies/mL) . | |||
|---|---|---|---|---|---|---|---|---|
| Initial . | Modification (mos)* . | Initial . | 1 y . | Initial . | 1 y . | |||
| I. Virologic responders† | ||||||||
| 1 | M | ddC/3TC | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (6) | 0 | 133 | 5.01 | < 1.7 |
| 2 | M | No | 3TC/d4T/IDV | No | 6 | 143 | 5.22 | < 1.7 |
| 3 | M | ZDV/3TC | 3TC/d4T/IDV | No | 7 | 217 | 4.63 | < 1.7 |
| 4 | M | ZDV/3TC | 3TC/d4T/IDV | No | 8 | 358 | 5.24 | 2.92 |
| 5 | M | ddC | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (6) | 10 | 200 | 4.48 | 1.74 |
| 6 | M | ddI/ddC | 3TC/d4T/IDV | No | 10 | 63 | 5.11 | 2.50 |
| 7 | F | ZDV/ddC | 3TC/d4T/IDV | No | 24 | 88 | 4.29 | < 1.7 |
| 8 | M | No | 3TC/d4T/IDV | No | 25 | 97 | 4.92 | < 1.7 |
| 9 | M | No | 3TC/d4T/IDV | No | 42 | 282 | 5.12 | 2.11 |
| 10 | M | ZDV/ddC | 3TC/d4T/IDV | No | 53 | 228 | 4.15 | < 1.7 |
| 11 | M | No | 3TC/d4T/IDV | No | 59 | 195 | 4.04 | < 1.7 |
| 12 | M | ZDV/ddC | 3TC/d4T/IDV | ZDV/3TC/IDV (6) | 60 | 253 | 4.27 | 2.11 |
| 13 | M | No | 3TC/d4T/IDV | No | 66 | 256 | 4.88 | < 1.7 |
| 14 | M | ZDV/3TC | 3TC/d4T/IDV | No | 67 | 197 | 4.09 | < 1.7 |
| 15 | M | ddI/3TC | 3TC/d4T/IDV | No | 70 | 149 | 4.27 | < 1.7 |
| 16 | F | ZDV/3TC | 3TC/d4T/IDV | No | 73 | 125 | 4.10 | < 1.7 |
| 17 | M | ddI/ddC | 3TC/d4T/IDV | No | 76 | 107 | 4.00 | < 1.7 |
| 18 | M | ZDV/3TC | 3TC/d4T/IDV | No | 82 | 207 | 4.75 | < 1.7 |
| 19 | F | ddI/ddC | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (6) | 84 | 218 | 4.36 | 2.29 |
| 20 | M | ZDV/3TC | 3TC/d4T/IDV | No | 100 | 342 | 4.76 | < 1.7 |
| 21 | M | No | 3TC/d4T/IDV | No | 114 | 290 | 5.19 | < 1.7 |
| 22 | M | 3TC/d4T | 3TC/d4T/IDV | No | 115 | 246 | 4.21 | < 1.7 |
| 23 | M | No | 3TC/d4T/IDV | No | 124 | 332 | 5.54 | < 1.7 |
| 24 | M | ddI/ddC | 3TC/d4T/IDV | No | 125 | 292 | 4.37 | < 1.7 |
| 25 | M | No | 3TC/d4T/IDV | No | 126 | 395 | 5.12 | < 1.7 |
| 26 | F | ddC | 3TC/d4T/IDV | No | 126 | 239 | 4.23 | < 1.7 |
| 27 | M | ZDV/ddI | 3TC/d4T/IDV | No | 129 | 285 | 4.41 | 2.23 |
| 28 | M | ZDV/ddI | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (6) | 141 | 101 | 4.25 | < 1.7 |
| 29 | F | No | 3TC/d4T/IDV | No | 150 | 564 | 5.85 | 1.7 |
| 30 | M | ZDV/ddI | 3TC/d4T/IDV | No | 167 | 247 | 4.60 | < 1.7 |
| 31 | M | No | 3TC/d4T/IDV | No | 168 | 222 | 4.17 | < 1.7 |
| 32 | M | ZDV/ddC | 3TC/d4T/IDV | No | 172 | 199 | 5.05 | < 1.7 |
| 33 | F | No | 3TC/d4T/IDV | No | 174 | 512 | 5.10 | < 1.7 |
| 34 | F | No | 3TC/d4T/IDV | No | 177 | 188 | 5.33 | < 1.7 |
| 35 | F | ddI/ddC | 3TC/d4T/IDV | ZDV/3TC/IDV (1) | 180 | 357 | 4.79 | < 1.7 |
| 36 | M | ZDV/ddI | 3TC/d4T/IDV | No | 182 | 387 | 4.11 | < 1.7 |
| 37 | F | No | 3TC/d4T/IDV | No | 194 | 396 | 4.52 | < 1.7 |
| 38 | M | ddI/ddC | 3TC/d4T/IDV | No | 212 | 417 | 4.79 | < 1.7 |
| 39 | M | ZDV/ddI | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (5) | 215 | 300 | 4.05 | 2.79 |
| 40 | M | No | 3TC/d4T/IDV | No | 219 | 366 | 4.41 | 2.42 |
| 41 | M | No | 3TC/d4T/IDV | No | 253 | 307 | 5.18 | < 1.7 |
| 42 | M | ddC/3TC | 3TC/d4T/IDV | No | 253 | 534 | 4.45 | < 1.7 |
| 43 | M | ZDV/ddC | 3TC/d4T/IDV | No | 259 | 381 | 4.15 | < 1.7 |
| 44 | M | No | 3TC/d4T/IDV | No | 259 | 358 | 4.55 | < 1.7 |
| 45 | M | ZDV/ddi | 3TC/d4T/IDV | ZDV/3TC/IDV (5) | 262 | 487 | 4.10 | < 1.7 |
| 46 | M | ddI/ddC | 3TC/d4T/IDV | No | 265 | 498 | 4.16 | < 1.7 |
| 47 | M | ddC | 3TC/d4T/IDV | No | 272 | 327 | 4.09 | 1.7 |
| 48 | M | ZDV/3TC | 3TC/d4T/IDV | No | 274 | 587 | 4.40 | < 1.7 |
| 49 | M | No | 3TC/d4T/IDV | No | 280 | 422 | 4.70 | < 1.7 |
| 50 | M | No | 3TC/d4T/IDV | No | 291 | 725 | 4.33 | < 1.7 |
| 51 | M | No | 3TC/d4T/IDV | No | 312 | 360 | 4.00 | < 1.7 |
| 52 | M | No | 3TC/d4T/IDV | No | 321 | 452 | 4.23 | 2.70 |
| 53 | M | No | 3TC/d4T/IDV | No | 339 | 471 | 5.09 | < 1.7 |
| 54 | M | ZDV/ddI | 3TC/d4T/IDV | No | 343 | 642 | 5.43 | < 1.7 |
| 55 | M | No | 3TC/d4T/IDV | No | 345 | 605 | 4.67 | < 1.7 |
| 56 | M | No | 3TC/d4T/IDV | No | 363 | 730 | 4.25 | 2.12 |
| 57 | M | ZDV/ddC | 3TC/d4T/IDV | No | 386 | 672 | 4.26 | < 1.7 |
| 58 | M | No | 3TC/d4T/IDV | No | 512 | 938 | 4.17 | < 1.7 |
| 59 | F | ddI/ddC | 3TC/d4T/IDV | No | 683 | 828 | 4.16 | < 1.7 |
| II. Virologic transient responders‡ | ||||||||
| 60 | M | ZDV/ddC | 3TC/d4T/IDV | ZDV/3TC/IDV (6) | 4 | 119 | 4.23 | 3.11 |
| 61 | F | ZDV/ddC | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (6) | 6 | 176 | 4.14 | 4.33 |
| 62 | M | ZDV/3TC | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (6) | 10 | 95 | 4.61 | 3.74 |
| 63 | M | No | 3TC/d4T/IDV | No | 17 | 378 | 5.05 | 3.70 |
| 64 | M | ZDV/ddC | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (8) | 61 | 291 | 4.38 | 4.53 |
| 65 | M | ddC/d4T | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (8) | 65 | 224 | 4.44 | 4.11 |
| 66 | M | ZDV/ddC | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (7) | 78 | 155 | 4.81 | 3.12 |
| 67 | M | No | 3TC/d4T/IDV | No | 88 | 365 | 5.00 | 4.54 |
| 68 | F | ddI/ddC | 3TC/d4T/IDV | No | 105 | 175 | 5.49 | 3.11 |
| 69 | F | ddC/d4T | 3TC/d4T/IDV | No | 109 | 176 | 4.24 | 3.53 |
| 70 | M | ddI/ddC | 3TC/d4T/IDV | No | 114 | 324 | 4.99 | 3.81 |
| 71 | M | No | 3TC/d4T/IDV | No | 115 | 266 | 4.38 | 4.21 |
| 72 | M | ZDV | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (5) | 117 | 185 | 4.71 | 4.40 |
| 73 | M | No | 3TC/d4T/IDV | No | 146 | 251 | 4.09 | 3.00 |
| 74 | M | No | 3TC/d4T/IDV | No | 203 | 223 | 4.05 | 4.81 |
| 75 | F | ddI/ddC | 3TC/d4T/IDV | No | 244 | 307 | 4.95 | 5.11 |
| 76 | M | ZDV/ddI | 3TC/d4T/IDV | No | 257 | 464 | 4.82 | 4.11 |
| 77 | M | No | 3TC/d4T/IDV | No | 279 | 548 | 5.07 | 3.23 |
| 78 | M | No | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (6) | 286 | 453 | 5.27 | 3.22 |
| 79 | M | No | 3TC/d4T/IDV | No | 292 | 452 | 5.08 | 3.15 |
| 80 | M | ZDV/ddC | 3TC/d4T/IDV | No | 294 | 372 | 4.10 | 3.70 |
| 81 | M | ZDV/ddC | 3TC/d4T/IDV | No | 324 | 454 | 4.30 | 3.60 |
| 82 | M | No | 3TC/d4T/IDV | No | 571 | 506 | 4.61 | 5.70 |
| III. Virologic non responders1-153 | ||||||||
| 83 | M | ZDV/ddI | 3TC/d4T/IDV | No | 0 | 45 | 5.01 | 4.11 |
| 84 | M | ZDV/ddC | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (7) | 2 | 27 | 4.90 | 4.52 |
| 85 | M | ZDV/ddC | 3TC/d4T/IDV | No | 2 | 17 | 5.56 | 5.01 |
| 86 | M | ZDV/ddC | 3TC/d4T/IDV | No | 15 | 102 | 4.93 | 4.75 |
| 87 | M | ZDV/3TC | 3TC/d4T/IDV | No | 30 | 283 | 4.10 | 4.22 |
| 88 | M | ZDV/ddC | 3TC/d4T/IDV | ZDV/3TC/IDV (4) | 36 | 163 | 4.99 | 5.04 |
| 89 | M | ZDV/ddI | 3TC/d4T/IDV | No | 43 | 136 | 5.22 | 4.36 |
| 90 | M | ZDV/ddC | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (6) | 81 | 237 | 4.24 | 4.51 |
| 91 | M | ZDV/ddI | 3TC/d4T/IDV | No | 132 | 554 | 4.34 | 5.90 |
| 92 | M | 3TC/d4T | 3TC/d4T/IDV | No | 154 | 141 | 4.21 | 4.61 |
| 93 | M | ZDV/3TC | 3TC/d4T/IDV | No | 155 | 274 | 4.79 | 4.72 |
| 94 | F | 3TC | 3TC/d4T/IDV | No | 187 | 165 | 4.75 | 4.63 |
| 95 | M | ddI/ddC | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (8) | 194 | 277 | 4.19 | 5.03 |
| 96 | F | ZDV/ddI | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (7) | 213 | 329 | 4.47 | 4.10 |
| 97 | M | No | 3TC/d4T/IDV | ZDV/3TC/IDV (5) | 286 | 647 | 4.31 | 4.11 |
| 98 | M | ZDV/ddC | 3TC/d4T/IDV | ZDV/3TC/IDV (4) | 361 | 629 | 4.42 | 4.31 |
| 99 | M | ddI/ddC | 3TC/d4T/IDV | 3TC/d4T/RTV/SQV (8) | 430 | 539 | 5.13 | 4.67 |
HIV-1, human immunodeficiency virus type 1; HAART, highly active antiretroviral therapy; ZDV, zidovadine; ddI, didanosine; ddC, zalcitabine; 3TC, lamivudine; d4T, stavudine; IDV, indinavir; RTV, ritonavir; SQV, saquinavir.
Indicates the duration (mos) after which the initial HAART regimen was modified.
Patients who had a plasma viral load decrease (ie, less than 1000 or 3 log10 Eq copies/mL) through the 12 mos of the study.
Patients who had an initial plasma viral load decrease (ie, less than 1000 or 3 log10 Eq copies/mL) after 2 mos of HAART but had a viral load reincrease (ie, 1000 or 3 log10 Eq copies/mL) at 8 to 12 mos of treatment.
Patients whose plasma viral load remained 1000 or 3 log10Eq copies/mL throughout the 12 mos of the study.