L-NAME inhibits estrogen-stimulated NO release from granulocytes
| Cells . | Estrogen agonist, 10−9 mol/L . | L-NAME, μmol/L . | NO level, nmol/L . |
|---|---|---|---|
| Granulocytes | 17β-estradiol | — | 18.1 + 2.3 |
| Granulocytes | 17β-estradiol | 100 | 1.9 + 0.8 |
| Cells . | Estrogen agonist, 10−9 mol/L . | L-NAME, μmol/L . | NO level, nmol/L . |
|---|---|---|---|
| Granulocytes | 17β-estradiol | — | 18.1 + 2.3 |
| Granulocytes | 17β-estradiol | 100 | 1.9 + 0.8 |
The NO level is given as the mean plus or minus SEM. Each experiment was replicated 4 times. P < .01 in comparing NO release in the presence of L-NAME to that in the appropriate tissues without it.