Table 2.

Osmotic fragility test of wild-type and β-adducin −/− mice

C50 ± SD [% (wt/vol) NaCl]
+/+ Young 0.517 ± 0.016  
+/− Young  0.510 ± 0.010  
−/− Young  0.569 ± 0.015  
+/+ Old  0.501 ± 0.014  
+/− Old  0.545 ± 0.011  
−/− Old  0.585 ± 0.025 
C50 ± SD [% (wt/vol) NaCl]
+/+ Young 0.517 ± 0.016  
+/− Young  0.510 ± 0.010  
−/− Young  0.569 ± 0.015  
+/+ Old  0.501 ± 0.014  
+/− Old  0.545 ± 0.011  
−/− Old  0.585 ± 0.025 

Five animals of each group were analyzed, and the reported values correspond to the mean values. The experiment was repeated 2 times with similar results. +/+ and −/− indicate normal littermate controls and β-adducin mutant animals, respectively. Young and Old indicate 2- to 4-month-old and 8- to 9-month-old animals, respectively.

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