Presence of c-kit+c-fms+cells in peripheral blood after candida infection
| Genotype . | Leukocytes (109/L) . | c-kit+c-fmslo cells (%) . |
|---|---|---|
| Wild-type | 9.2 ± 2.7 | 3.8 ± 1.8 |
| G-CSF−/− | 7.7 ± 1.8 | 12.1 ± 4.15-150 |
| G-CSF−/−/GM-CSF−/− | 6.8 ± 1.4 | 11.4 ± 1.15-150 |
| G-CSF−/−/IL-6−/− | 6.0 ± 0.7 | 10.3 ± 3.25-150 |
| Genotype . | Leukocytes (109/L) . | c-kit+c-fmslo cells (%) . |
|---|---|---|
| Wild-type | 9.2 ± 2.7 | 3.8 ± 1.8 |
| G-CSF−/− | 7.7 ± 1.8 | 12.1 ± 4.15-150 |
| G-CSF−/−/GM-CSF−/− | 6.8 ± 1.4 | 11.4 ± 1.15-150 |
| G-CSF−/−/IL-6−/− | 6.0 ± 0.7 | 10.3 ± 3.25-150 |
Presence of progenitor cells in circulation was studied by staining WBC with antibodies against c-fms and c-kit. Cells were analyzed on FACScan using CellQuest software and total WBC count was determined by Sysmex K-1000.
Data are represented as mean ± SD. Ten to 12 mice of each genotype were analyzed.
P < .05 compared to wild-type mice.