Structural characteristics, location, and putative functions of ALL1/MLL/HRX partner genes
| Partner gene . | Chromosomal location . | Transcript size (kb) . | Protein size (aa) . | Putative function . | Shared homology . | References . |
|---|---|---|---|---|---|---|
| AF4 or FEL | 4q21 | 12 and 15 | 1200 | Transcription factor | None | 61, 62 |
| AF9 | 9p22 | 5 | 578 | Transcription factor | ENL | 61 |
| ENL | 19p13 | 4.7 | 559 | Transcription factor | AF9 | 61, 64 |
| AF6 | 6q27 | 8 | 1612 | Cytoplasmic protein | None | 63 |
| AF1p | 1p32 | 4.4 | 896 | Cytoplasmic protein | None | 70 |
| AF10 | 10p12 | 5.5 | 1027 | Cytoplasmic protein | AF17 | 72 |
| AF17 | 17q21 | 7.5 and 5 | 1093 | Dimerization protein | AF10 | 66 |
| ELL | 19p13.1 | 4.4 | 621 | Transcription factor | None | 65 |
| AF1q | 1q21 | 1.7 | 90 | Growth factor | None | 69 |
| AFX1 | Xq13 | Not determined | Not determined | Transcription factor | AF6q21 | 68 |
| CBP | 16p13 | 9 | 2491 | Transcriptional coactivator | None | 71 |
| AF6q21 | 6q21 | 6 | 403 | Transcription factor | AFX | 77 |
| ENN | 19p13 | 2.6 | 368 | Cytoplasmic protein | None | 72 |
| ABI-1 | 10p11.2 | 2.9 | 387 | Cytoplasmic protein | None | 75 |
| HCDCrel | 22q11.2 | 2.5 and 3.5 | 369 | Cytoplasmic protein | MSF | 74 |
| MSF | 17q25 | 2.8 | 568 | Cytoplasmic protein | HCDCrel | 76 |
| Partner gene . | Chromosomal location . | Transcript size (kb) . | Protein size (aa) . | Putative function . | Shared homology . | References . |
|---|---|---|---|---|---|---|
| AF4 or FEL | 4q21 | 12 and 15 | 1200 | Transcription factor | None | 61, 62 |
| AF9 | 9p22 | 5 | 578 | Transcription factor | ENL | 61 |
| ENL | 19p13 | 4.7 | 559 | Transcription factor | AF9 | 61, 64 |
| AF6 | 6q27 | 8 | 1612 | Cytoplasmic protein | None | 63 |
| AF1p | 1p32 | 4.4 | 896 | Cytoplasmic protein | None | 70 |
| AF10 | 10p12 | 5.5 | 1027 | Cytoplasmic protein | AF17 | 72 |
| AF17 | 17q21 | 7.5 and 5 | 1093 | Dimerization protein | AF10 | 66 |
| ELL | 19p13.1 | 4.4 | 621 | Transcription factor | None | 65 |
| AF1q | 1q21 | 1.7 | 90 | Growth factor | None | 69 |
| AFX1 | Xq13 | Not determined | Not determined | Transcription factor | AF6q21 | 68 |
| CBP | 16p13 | 9 | 2491 | Transcriptional coactivator | None | 71 |
| AF6q21 | 6q21 | 6 | 403 | Transcription factor | AFX | 77 |
| ENN | 19p13 | 2.6 | 368 | Cytoplasmic protein | None | 72 |
| ABI-1 | 10p11.2 | 2.9 | 387 | Cytoplasmic protein | None | 75 |
| HCDCrel | 22q11.2 | 2.5 and 3.5 | 369 | Cytoplasmic protein | MSF | 74 |
| MSF | 17q25 | 2.8 | 568 | Cytoplasmic protein | HCDCrel | 76 |