Patient characteristics
. | All patients (n = 1329) . | Patients with S pneumoniae sepsis (n = 31) . |
---|---|---|
Median age (y) at BMT (range, y) | 25 (1-61) | 22 (2-49) |
Sex (M/F) | 800/529 | 19/12 |
Diagnosis | ||
Acute myeloid leukemia | 615 | 18 |
Acute lymphoblastic leukemia | 339 | 7 |
Chronic myeloid leukemia | 143 | 2 |
Other | 232 | 3 |
Median time (mo) from BMT (range, mo) | 10 (3-187) | |
Type of BMT | ||
Allograft | 918 | 26 |
Donor | ||
Matched sibling | 754 | 24 |
Mismatched family | 91 | 0 |
Matched unrelated | 73 | 2 |
Total-body irradiation | ||
Yes | 755 | 22 |
No | 163 | 4 |
GVHD prophylaxis | ||
Cyclosporine alone | 525 | 21 |
Methotrexate ± cyclosporine | 393 | 5 |
Autograft | 411 | 5 |
Total-body irradiation | ||
Yes | 284 | 5 |
No | 127 | 0 |
Conditioning regimen | ||
Total-body irradiation | 1039 | 27 |
Chemotherapy only | 290 | 4 |
. | All patients (n = 1329) . | Patients with S pneumoniae sepsis (n = 31) . |
---|---|---|
Median age (y) at BMT (range, y) | 25 (1-61) | 22 (2-49) |
Sex (M/F) | 800/529 | 19/12 |
Diagnosis | ||
Acute myeloid leukemia | 615 | 18 |
Acute lymphoblastic leukemia | 339 | 7 |
Chronic myeloid leukemia | 143 | 2 |
Other | 232 | 3 |
Median time (mo) from BMT (range, mo) | 10 (3-187) | |
Type of BMT | ||
Allograft | 918 | 26 |
Donor | ||
Matched sibling | 754 | 24 |
Mismatched family | 91 | 0 |
Matched unrelated | 73 | 2 |
Total-body irradiation | ||
Yes | 755 | 22 |
No | 163 | 4 |
GVHD prophylaxis | ||
Cyclosporine alone | 525 | 21 |
Methotrexate ± cyclosporine | 393 | 5 |
Autograft | 411 | 5 |
Total-body irradiation | ||
Yes | 284 | 5 |
No | 127 | 0 |
Conditioning regimen | ||
Total-body irradiation | 1039 | 27 |
Chemotherapy only | 290 | 4 |
The autograft group included 19 recipients of syngeneic transplants, 1 of whom had pneumococcal sepsis.