Clonal outgrowth of lymphoma cells treated with either VP-16 alone or VP-16 in the presence of H2O2
| Treatment . | No. of surviving clones (%) . |
|---|---|
| Experiment 1 | |
| VP-16 alone | 2 (0.7) |
| VP-16 + 50 μmol/L H2O2 | 4 (1.4) |
| Experiment 2 | |
| VP-16 alone | 6 (2.1) |
| VP-16 + 50 μmol/L H2O2 | 9 (3.1) |
| Treatment . | No. of surviving clones (%) . |
|---|---|
| Experiment 1 | |
| VP-16 alone | 2 (0.7) |
| VP-16 + 50 μmol/L H2O2 | 4 (1.4) |
| Experiment 2 | |
| VP-16 alone | 6 (2.1) |
| VP-16 + 50 μmol/L H2O2 | 9 (3.1) |
JLP 119 cells were treated for 12 h with 1 μg/mL VP-16 alone or in the presence of 50 μmol/L H2O2. Remaining live cells were counted, diluted in fresh culture medium, and plated in 96-well plates at 3 cells/well (288 wells per treatment). The number and percentage of wells containing cellular outgrowth after 3 weeks of culture are shown.