Table 3.

Percent donor composition of BM after serial transplantation

GenotypePrimary Secondary Tertiary
Wild-type  94.0 ± 0.7 87.4 ± 7.2  59.3 ± 13.4  
Transgene  92.2 ± 0.6 75.9 ± 8.5  63.5 ± 14.8  
P value  (.60) (.34)  (.84) 
GenotypePrimary Secondary Tertiary
Wild-type  94.0 ± 0.7 87.4 ± 7.2  59.3 ± 13.4  
Transgene  92.2 ± 0.6 75.9 ± 8.5  63.5 ± 14.8  
P value  (.60) (.34)  (.84) 

Mean (±SEM) percent Ly5.2 cells recovered, normalized to equal numbers of donor cells transferred. Numbers of animals of each genotype per group were 5-7. P values are for differences between wild-type and transgene donor engraftment, as represented by percent Ly5.2 cells.

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