Bone marrow colonies
| . | Marrow colonies/104low-density cells . | Colonies/0.5 × 105 low-density cells CFU-Mk . | ||
|---|---|---|---|---|
| BFU-E . | CFU-GM . | CFU-GEMM . | ||
| Unaffected (IV-8)* | 39.5 + 4.7 | 18.8 + 5.0 | 13.1 + 6.3 | 58 |
| Affected (IV-10)* | 75.7 + 11.2 | 27.1 + 7.6 | 22.9 + 9.1 | 155† |
| Affected (V-14)* | 64.5 + 15.6 | 17.3 + 3.9 | 16.0 + 5.2 | 123† |
| . | Marrow colonies/104low-density cells . | Colonies/0.5 × 105 low-density cells CFU-Mk . | ||
|---|---|---|---|---|
| BFU-E . | CFU-GM . | CFU-GEMM . | ||
| Unaffected (IV-8)* | 39.5 + 4.7 | 18.8 + 5.0 | 13.1 + 6.3 | 58 |
| Affected (IV-10)* | 75.7 + 11.2 | 27.1 + 7.6 | 22.9 + 9.1 | 155† |
| Affected (V-14)* | 64.5 + 15.6 | 17.3 + 3.9 | 16.0 + 5.2 | 123† |
Mean ± standard deviation of 5 plates for BFU-E, CFU-GM, and CFU-GEMM. CFU-Mk data is the average of 2 separate slide chambers.
Numbers in parentheses indicate patient identifier (Figure 1).
Numbers for affected individuals are likely to be underestimates because confluent colonies were difficult to distinguish.