Table 1.

Expression of DYRK2 and REDK in hematopoietic tissues and cell lines

Tissue/Cells DYRK2 REDK
Bone marrow −  ++  
Fetal liver  −  +++  
PBLs  −  − 
Stroma  −  −  
TF274  +++  −  
Myeloid −  −  
 KG1a, HL60  
Monocytic U937, THP-1  − −  
Erythroleukemic K562, HEL  −  ++  
EPO-responsive UT7-EPO, TF1  −  +++  
Megakaryoblastic Mo7e, CMK  − −  
Lymphocytic Bjab, Supt-1, Jurkat  ±  −  
Cancer lines  −  −  
 A549, HeLa, MRC5 
Tissue/Cells DYRK2 REDK
Bone marrow −  ++  
Fetal liver  −  +++  
PBLs  −  − 
Stroma  −  −  
TF274  +++  −  
Myeloid −  −  
 KG1a, HL60  
Monocytic U937, THP-1  − −  
Erythroleukemic K562, HEL  −  ++  
EPO-responsive UT7-EPO, TF1  −  +++  
Megakaryoblastic Mo7e, CMK  − −  
Lymphocytic Bjab, Supt-1, Jurkat  ±  −  
Cancer lines  −  −  
 A549, HeLa, MRC5 

cDNA probes for DYRK2 and REDK were hybridized to dot blots containing equivalent amounts of pAK + RNA from the human tissues and cells shown. Signals above background were ranked as ±, +, ++, or +++.

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