MDR status of AML blasts and the TF1 and U937 cell lines
| . | Pgp D Value . | R123+/-PSC-833 Modulation Ratio . | Daunorubicin Cell:Bead Ratio . |
|---|---|---|---|
| pgp protein positive | |||
| GO | 0.34 | 3.2 | 1.5 |
| JD | 0.33 | 2.4 | 1.9 |
| RF | 0.47 | 1.3 | 2.0 |
| DS | 0.19 | 2.7 | 1.1 |
| BB | 0.15 | 3.0 | 2.2 |
| TF1 cell line | 0.93 ± 0.03 | 5.0 ± 0.47 | ND |
| pgp protein negative | |||
| CL | 0.02 | 1.5 | 1.8 |
| AJ | 0.05 | 1.1 | 2.9 |
| JK | 0.05 | 2.0 | 2.25 |
| AC | 0.08 | 1.4 | 2.1 |
| GM | 0.03 | 1.6 | 2.7 |
| LC | 0.02 | 1.9 | 1.4 |
| U937 cell line | 0.037 ± 0.02 | 1.12 ± 0.01 | ND |
| . | Pgp D Value . | R123+/-PSC-833 Modulation Ratio . | Daunorubicin Cell:Bead Ratio . |
|---|---|---|---|
| pgp protein positive | |||
| GO | 0.34 | 3.2 | 1.5 |
| JD | 0.33 | 2.4 | 1.9 |
| RF | 0.47 | 1.3 | 2.0 |
| DS | 0.19 | 2.7 | 1.1 |
| BB | 0.15 | 3.0 | 2.2 |
| TF1 cell line | 0.93 ± 0.03 | 5.0 ± 0.47 | ND |
| pgp protein negative | |||
| CL | 0.02 | 1.5 | 1.8 |
| AJ | 0.05 | 1.1 | 2.9 |
| JK | 0.05 | 2.0 | 2.25 |
| AC | 0.08 | 1.4 | 2.1 |
| GM | 0.03 | 1.6 | 2.7 |
| LC | 0.02 | 1.9 | 1.4 |
| U937 cell line | 0.037 ± 0.02 | 1.12 ± 0.01 | ND |
Values for TF1 and U937 cell lines are given as mean ±SD.
ND indicates not determined.