Summary of BCL10 cDNA sequence... | American Society of Hematology

Summary of BCL10 cDNA sequence abnormalities in 3PBL and 3FCL

		Clone No.	Alteration	Coding Exon	Codon	Mutation Type	Size (Full Length = 233aa)
Normal	1	1	400T → C	3	134	Ser → Pro	233aa
PBL		2	nil				233aa
		3	136delA	2	46	Truncation	68aa
		4	114T → C	2	38	Silent
			501T → C	3	167	Silent	233aa
			655A → G	3	219	Ser → Gly
		5	152A → G	2	51	Asp → Gly	233aa
	2	1	39C → T	1	13	Silent	233aa
		2	64G → T	2	22	Truncation	21aa
		3	272insA	2	91	Truncation	101aa
		4	137insA	2	46	Truncation	48aa
		5	33G → T	1	11	Glu → Asp	233aa
	3	1	137insA	2	46	Truncation	48aa
		2	89A → G	2	30	Glu → Gly
			136delA	2	46	Truncation	68aa
		3	386C → T	3	129	Silent
			453T → C	3	151	Silent	233aa
			638G → A	3	213	Gly → Glu
		4	136delA	2	46	Truncation	68aa
		5	24G → C	1	8	Silent	68aa
			136delA	2	46	Truncation
FCL	1	1	272insA	2	91	Truncation	101aa
		2	157G → A	2	53	Glu → Lys	233aa
		3	195T → A	2	65	Silent	233aa
		4	321A → G	2	107	Silent	168aa
			500insT	3	167	Truncation
		5	500insT	3	167	Truncation	168aa
	2	1	521T → A	3	174	Truncation	173aa
		2	136delA	2	46	Truncation	68aa
		3	nil				233aa
		4	137insA	2	46	Truncation	48aa
		5	nil				233aa
	3	1	nil				233aa
		2	135A → G	2	45	Silent
			317T → C	2	106	Leu → Pro	178aa
			504del118	3	168-208	Deletion
		3	500insT	3	167	Truncation	168aa
		4	470A → G	3	157	Glu → Gly
			476A → G	3	159	Glu → Gly	168aa
			500insT	3	167	Truncation
		5	nil				233aa

		Clone No.	Alteration	Coding Exon	Codon	Mutation Type	Size (Full Length = 233aa)
Normal	1	1	400T → C	3	134	Ser → Pro	233aa
PBL		2	nil				233aa
		3	136delA	2	46	Truncation	68aa
		4	114T → C	2	38	Silent
			501T → C	3	167	Silent	233aa
			655A → G	3	219	Ser → Gly
		5	152A → G	2	51	Asp → Gly	233aa
	2	1	39C → T	1	13	Silent	233aa
		2	64G → T	2	22	Truncation	21aa
		3	272insA	2	91	Truncation	101aa
		4	137insA	2	46	Truncation	48aa
		5	33G → T	1	11	Glu → Asp	233aa
	3	1	137insA	2	46	Truncation	48aa
		2	89A → G	2	30	Glu → Gly
			136delA	2	46	Truncation	68aa
		3	386C → T	3	129	Silent
			453T → C	3	151	Silent	233aa
			638G → A	3	213	Gly → Glu
		4	136delA	2	46	Truncation	68aa
		5	24G → C	1	8	Silent	68aa
			136delA	2	46	Truncation
FCL	1	1	272insA	2	91	Truncation	101aa
		2	157G → A	2	53	Glu → Lys	233aa
		3	195T → A	2	65	Silent	233aa
		4	321A → G	2	107	Silent	168aa
			500insT	3	167	Truncation
		5	500insT	3	167	Truncation	168aa
	2	1	521T → A	3	174	Truncation	173aa
		2	136delA	2	46	Truncation	68aa
		3	nil				233aa
		4	137insA	2	46	Truncation	48aa
		5	nil				233aa
	3	1	nil				233aa
		2	135A → G	2	45	Silent
			317T → C	2	106	Leu → Pro	178aa
			504del118	3	168-208	Deletion
		3	500insT	3	167	Truncation	168aa
		4	470A → G	3	157	Glu → Gly
			476A → G	3	159	Glu → Gly	168aa
			500insT	3	167	Truncation
		5	nil				233aa

Abbreviations: PBL, peripheral blood leukocytes; FCL, follicular lymphoma; aa, amino acid.