NGF production by HHV-8+ and HHV-8− B-lymphoma cells
| Cell Lines . | HHV-8 . | EBV . | NGF, pg/mL . | |
|---|---|---|---|---|
| 24 h . | 48 h . | |||
| BC-1 | + | + | 550 ± 36 | 480 ± 51 |
| BC-1 + Na butyrate | 186 ± 15 | 1500 ± 125 | ||
| BCBL-1 | + | − | 480 ± 55 | 336 ± 34 |
| BCBL-1 + TPA | 144 ± 15 | 1200 ± 86 | ||
| RAMOS | − | − | UD | UD |
| RAMOS + TPA | UD | UD | ||
| RAMOS + Na butyrate | UD | UD | ||
| Cell Lines . | HHV-8 . | EBV . | NGF, pg/mL . | |
|---|---|---|---|---|
| 24 h . | 48 h . | |||
| BC-1 | + | + | 550 ± 36 | 480 ± 51 |
| BC-1 + Na butyrate | 186 ± 15 | 1500 ± 125 | ||
| BCBL-1 | + | − | 480 ± 55 | 336 ± 34 |
| BCBL-1 + TPA | 144 ± 15 | 1200 ± 86 | ||
| RAMOS | − | − | UD | UD |
| RAMOS + TPA | UD | UD | ||
| RAMOS + Na butyrate | UD | UD | ||
Results represent the mean (± SD) of 3 independent experiments with 1 × 107 cells/mL; NGF was measured in the conditioned media as described in “Materials and methods.” UD indicates undetectable.