Table 3.

Multivariate analysis of prognostic factors for survival in 44 patients with T-MF

Characteristics Univariate Analysis Multivariate Analysis (final model)
HR PHR (95% CI) P
Age 
 Younger than 60 y  1.00   1.00  
 At least 60 y 2.10  .11  2.81 (1.03-7.61)  .04  
Sex  
 Male 1.00  
 Female  0.51  .11  
Clinical stage 
 IIb  1.00   1.00  
 IV  1.96  .10 2.22 (0.99-4.98)  .05  
Stage of skin disease  
 T2 1.00  
 T3  0.49  .26  
Delay MF/T-MF  
 Less than 2 y  1.00  
 At least 2 y  0.62  .33 
Extracutaneous spreading (follow-up)  
 Yes  1.00 
 No  2.49  .02  
% of large cells  
 25%-49% 1.00  
 50%-79%  0.51  .32  
 80%-100%  0.45 .25  
CD30 expression  
 No staining  1.00 
 Positivity at less than 75%  0.39  .14  
 Positivity at 75% or more  0.43  .18 
Characteristics Univariate Analysis Multivariate Analysis (final model)
HR PHR (95% CI) P
Age 
 Younger than 60 y  1.00   1.00  
 At least 60 y 2.10  .11  2.81 (1.03-7.61)  .04  
Sex  
 Male 1.00  
 Female  0.51  .11  
Clinical stage 
 IIb  1.00   1.00  
 IV  1.96  .10 2.22 (0.99-4.98)  .05  
Stage of skin disease  
 T2 1.00  
 T3  0.49  .26  
Delay MF/T-MF  
 Less than 2 y  1.00  
 At least 2 y  0.62  .33 
Extracutaneous spreading (follow-up)  
 Yes  1.00 
 No  2.49  .02  
% of large cells  
 25%-49% 1.00  
 50%-79%  0.51  .32  
 80%-100%  0.45 .25  
CD30 expression  
 No staining  1.00 
 Positivity at less than 75%  0.39  .14  
 Positivity at 75% or more  0.43  .18 

HR = hazard ratio; CI = confidence interval.

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