NKT cells and a memory-activated phenotype
| . | Cord Blood . | Adult Blood . | ||||
|---|---|---|---|---|---|---|
| T Cells . | NK Cells . | NKT Cells . | T Cells . | NK Cells . | NKT Cells . | |
| CD45RAbright | 64.4 ± 10.1 | 98.0 ± 2.7 | 9.4 ± 7.5* | 50.3 ± 5.4 | 97.1 ± 2.1 | 3.4 ± 1.3* |
| CD45RAdim | 33.2 ± 9.0 | 1.9 ± 2.8 | 42.9 ± 2.1 | 27.4 ± 6.2 | 2.7 ± 2.0 | 79.7 ± 8.2* |
| CD45RO | 25.4 ± 5.3 | 2.7 ± 2.7 | 93.7 ± 5.6* | 53.4 ± 8.4 | 3.7 ± 1.9 | 99.2 ± 0.7† |
| CD62L | 79.7 ± 18.7 | 22.6 ± 10.6 | 41.3 ± 16.3‡ | 67.9 ± 9.6 | 28.0 ± 10.5 | 15.4 ± 11.2‡ |
| CD69 | 0.2 ± 0.1 | 1.8 ± 2.6 | 0.5 ± 0.8 | 0.5 ± 0.3 | 1.5 ± 1.6 | 8.5 ± 8.9 |
| CD25 | 7.4 ± 2.8 | 1.3 ± 1.5 | 60.8 ± 23.8* | 17.0 ± 6.1 | 2.7 ± 1.7 | 55.7 ± 25.21-153 |
| . | Cord Blood . | Adult Blood . | ||||
|---|---|---|---|---|---|---|
| T Cells . | NK Cells . | NKT Cells . | T Cells . | NK Cells . | NKT Cells . | |
| CD45RAbright | 64.4 ± 10.1 | 98.0 ± 2.7 | 9.4 ± 7.5* | 50.3 ± 5.4 | 97.1 ± 2.1 | 3.4 ± 1.3* |
| CD45RAdim | 33.2 ± 9.0 | 1.9 ± 2.8 | 42.9 ± 2.1 | 27.4 ± 6.2 | 2.7 ± 2.0 | 79.7 ± 8.2* |
| CD45RO | 25.4 ± 5.3 | 2.7 ± 2.7 | 93.7 ± 5.6* | 53.4 ± 8.4 | 3.7 ± 1.9 | 99.2 ± 0.7† |
| CD62L | 79.7 ± 18.7 | 22.6 ± 10.6 | 41.3 ± 16.3‡ | 67.9 ± 9.6 | 28.0 ± 10.5 | 15.4 ± 11.2‡ |
| CD69 | 0.2 ± 0.1 | 1.8 ± 2.6 | 0.5 ± 0.8 | 0.5 ± 0.3 | 1.5 ± 1.6 | 8.5 ± 8.9 |
| CD25 | 7.4 ± 2.8 | 1.3 ± 1.5 | 60.8 ± 23.8* | 17.0 ± 6.1 | 2.7 ± 1.7 | 55.7 ± 25.21-153 |
Expression of cell-surface markers on T, NK, and NKT cells in cord and adult peripheral blood. Data represent mean percentage ± SD of positive cells within each cell population. NKT cells represented 0.08 ± 0.05% and 0.08 ± 0.04% of T cells in cord and adult peripheral blood, respectively.
Indicates significant compared to T cells (P < .0001) and NK cells (P < .0001).
Indicates significant compared to T cells (P = .0002) and NK cells (P < .0001).
Indicates significant compared to T cells (P < .0001).
Indicates significant compared to T cells (P = .0376) and NK cells (P = .0095).