Table 7.

Univariate analysis of correlation between preoperative variables and long-term complications in 223 patients with MMM who underwent splenectomy

Variable Blast transformation PSH PST
Indication for surgery  .88  .67  .42  
Type of MMM .72  .84  .92  
Hemoglobin < 90 g/L  .84  .91 .51  
White blood cell count  .61  .49  .72  
Platelet count < 100 × 109/L  .31  .20  .00017-150 
Platelet count < 50 × 109/L  .02  .92 .0097-151 
Splenic mass  .03  .19  .72  
Presence of circulating blasts  .81  .57  .64  
Bone marrow cellularity .39  .55  .71  
Bone marrow blast percentage  .38 1.0  1.0  
Fibrosis grade on reticulin staining  .60 .85  .30  
Presplenectomy cytogenetic abnormalities  .29 1.0  .77  
Red cell-transfusion requirement  .71  .91 .56 
Variable Blast transformation PSH PST
Indication for surgery  .88  .67  .42  
Type of MMM .72  .84  .92  
Hemoglobin < 90 g/L  .84  .91 .51  
White blood cell count  .61  .49  .72  
Platelet count < 100 × 109/L  .31  .20  .00017-150 
Platelet count < 50 × 109/L  .02  .92 .0097-151 
Splenic mass  .03  .19  .72  
Presence of circulating blasts  .81  .57  .64  
Bone marrow cellularity .39  .55  .71  
Bone marrow blast percentage  .38 1.0  1.0  
Fibrosis grade on reticulin staining  .60 .85  .30  
Presplenectomy cytogenetic abnormalities  .29 1.0  .77  
Red cell-transfusion requirement  .71  .91 .56 

All values are P values. PSH indicates postsplenectomy palpable hepatomegaly (liver palpable greater than 6 cm below the RCM); and PST, postsplenectomy thrombocytosis (platelet count greater than 600 × 109/L).

F7-150

Platelet count greater than 100 × 109/L.

F7-151

Platelet count greater than 50 × 109/L.

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