Results of PCR-based analysis of the EBV genotype of the normal viral carriers (VC1-15)
| Virus Carrier . | Sex/ Age . | Anatomic Sites . | Types T1/T2 . | LMP1 wt/del . | LMP1 Repeats . | BamHI F/f . | BamHI Z/Z* . |
|---|---|---|---|---|---|---|---|
| VC 1 | F/73 | Mediastinal lymph node | T1 | wt/del | 4.5 | — | — |
| Nasopharynx | T1 | wt/del | 4.5 | F | — | ||
| Larynx | — | wt/del | 5 | — | — | ||
| Anterior tongue | T1 | wt/del | 4 | — | — | ||
| Submandibular gland | T1 | del | 4.5 | — | — | ||
| Peripheral blood | — | wt/del | 5 | F | Z | ||
| VC 2 | F/89 | Mediastinal lymph node | T1 | wt/del | 4.5 | F/f | Z/Z* |
| Nasopharynx | T1 | del | 4.5 | F/f | Z* | ||
| Larynx | T1 | wt/del | 4.5 | — | Z* | ||
| Anterior tongue | T1 | wt/del | 4.5 | F/f | Z/Z* | ||
| Submandibular gland | T1 | wt/del | 4.5 | F/f | Z/Z* | ||
| Peripheral blood | T1 | wt/del | 4.5 | F/f | — | ||
| VC 3 | F/72 | Mediastinal lymph node | — | — | 6 | — | Z/Z* |
| Nasopharynx | T1 | wt/del | 6 | F | Z/Z* | ||
| Larynx | T1 | wt/del | 5/6 | F | Z/Z* | ||
| Anterior tongue | — | wt/del | 5 | — | Z/Z* | ||
| Submandibular gland | T1 | — | 6 | — | Z/Z* | ||
| Peripheral blood | T1 | del | 5 | F | Z/Z* | ||
| VC 4 | M/82 | Mediastinal lymph node | T1/T2 | wt/del | 4.5 | F | Z/Z* |
| Nasopharynx | T1/T2 | wt/del | — | F | Z/Z* | ||
| Larynx | T1/T2 | wt/del | 4.5 | F | Z* | ||
| Anterior tongue | T1/T2 | wt/del | 4.5 | F | Z* | ||
| Submandibular gland | T1/T2 | wt/del | 4.5 | F | Z* | ||
| Peripheral blood | T1/T2 | wt/del | 4.5 | F | Z* | ||
| VC 5 | M/77 | Mediastinal lymph node | T1 | del | 7 | F | — |
| Nasopharynx | T1 | wt/del | 4.5/7 | — | Z/Z* | ||
| Larynx | T1 | wt/del | 4.5/7 | F | Z/Z* | ||
| Anterior tongue | T1 | wt/del | 7 | F | Z/Z* | ||
| Submandibular gland | T1 | wt/del | 4.5/7 | F | Z/Z* | ||
| Peripheral blood | T1 | wt/del | 5/7 | — | Z | ||
| VC 6 | M/68 | Mediastinal lymph node | T1/T2 | wt/del | 4/5 | F | Z/Z* |
| Nasopharynx | T1/T2 | wt/del | 4/5 | F | Z/Z* | ||
| Larynx | T1/T2 | wt/del | 4/5 | F | Z/Z* | ||
| Anterior tongue | nd | nd | nd | nd | nd | ||
| Submandibular gland | T1/T2 | wt/del | 4/5 | F | Z/Z* | ||
| Peripheral blood | T1 | wt/del | 4/5 | F | Z/Z* | ||
| VC 7 | F/83 | Mediastinal lymph node | T1 | del | 7 | F | Z/Z* |
| Nasopharynx | T1/T2 | wt/del | 4.5/7 | F | Z/Z* | ||
| Larynx | T1 | wt/del | 4.5/7 | F | Z/Z* | ||
| Anterior tongue | T2 | wt/del | 7 | F | — | ||
| Submandibular gland | T2 | wt/del | 5/7 | F | Z/Z* | ||
| Peripheral blood | T1/T2 | wt/del | 5/7 | F | Z/Z* | ||
| VC 8 | M/57 | Cervical lymph node | T1 | wt/del | 4/4.5 | F | nd |
| Mediastinal lymph node | T1 | del | 4/4.5 | F | nd | ||
| Para-aortic lymph node | T1 | wt/del | — | F | nd | ||
| Nasopharynx | T1 | del | 4 | F | nd | ||
| Thyroid | T1 | wt/del | 4.5 | — | nd | ||
| Tonsil (palatine) | T1 | wt/del | 4/4.5 | F | nd | ||
| Submandibular gland | T1 | wt/del | 4.5 | — | nd | ||
| Spleen | T1 | wt/del | 4.5 | — | nd | ||
| Thymus | T1 | wt/del | — | — | nd | ||
| VC 9 | F/70 | Cervical lymph node | T1 | wt | 4.5 | F | nd |
| Mediastinal lymph node | T1 | wt | 4.5 | F | nd | ||
| Para-aortic lymph node | — | wt | — | F | nd | ||
| Nasopharynx | T1 | wt | 4.5 | F/f | nd | ||
| Thyroid | — | wt | 4.5 | — | nd | ||
| Tonsil (palatine) | T1 | wt | 4.5 | F | nd | ||
| Submandibular gland | — | wt | 4.5 | — | nd | ||
| Spleen | — | wt | 4.5 | — | nd | ||
| VC 10 | F/26 | Cervical lymph node | T1 | — | 4.5/5 | F/f | nd |
| Mediastinal lymph node | — | — | 4.5 | F/f | nd | ||
| Para-aortic lymph node | T1 | — | 4.5 | — | nd | ||
| Nasopharynx | T1 | — | 4.5/5 | F/f | nd | ||
| Thyroid | T1 | — | 4.5 | — | nd | ||
| Tonsil (palatine) | T1 | wt/del | 4.5/5 | F/f | nd | ||
| Tonsil (lingual) | T1 | wt/del | 4.5 | — | nd | ||
| Lung (central) | T1/T2 | del | 4.5 | — | nd | ||
| Lung (peripheral) | T1 | del | 4.5 | — | nd | ||
| Spleen | T1 | — | 4.5 | — | nd | ||
| Thymus | T1 | — | 4.5 | — | nd | ||
| VC 11 | M/40 | Cervical lymph node | T1 | wt/del | — | — | nd |
| Nasopharynx | T1/T2 | wt/del | 4.5 | F/f | nd | ||
| Larynx | T1 | wt | 4.5/5/6 | — | nd | ||
| Oropharynx | T1 | — | 4.5 | — | nd | ||
| Tonsil | T1 | wt | 4.5 | — | nd | ||
| Parotid gland | — | wt/del | — | F | nd | ||
| Submandibular gland | T1 | del | 4/4.5/5/6 | F | nd | ||
| Penis | T1 | wt | 4.5/5/6 | — | nd | ||
| VC 12 | M/33 | Cervical lymph node | — | wt/del | — | — | nd |
| Nasopharynx | T1 | wt/del | 4.5/5 | F | nd | ||
| Larynx | — | del | — | — | nd | ||
| Oropharynx | — | wt/del | — | — | nd | ||
| Tonsil | — | del | 4.5 | F/f | nd | ||
| Parotid gland | T1 | del | 4.5 | — | nd | ||
| Submandibular gland | T1 | del | 4.5 | — | nd | ||
| Penis | — | del | — | F/f | nd | ||
| VC 13 | M/69 | Cervical lymph node | T1 | wt/del | 4.5 | F/f | nd |
| Nasopharynx | T1 | del | 4/4.5/5/6 | F/f | nd | ||
| Larynx | — | wt/del | — | — | nd | ||
| Oropharynx | — | wt/del | — | — | nd | ||
| Tonsil | T1 | wt/del | 4.5 | F/f | nd | ||
| Parotid gland | T1/T2 | wt/del | 4.5 | F | nd | ||
| Submandibular gland | T1 | wt/del | 4.5 | — | nd | ||
| Penis | T1 | wt/del | 4.5 | — | nd | ||
| VC 14 | M/88 | Cervical lymph node | T1/T2 | del | 4.5/5/6 | F | nd |
| Mediastinal lymph node | T1 | del | 5/6 | F | nd | ||
| Para-aortic lymph node | T1 | del | 5/6 | F | nd | ||
| Thyroid | T1 | del | 4.5 | F | nd | ||
| Lung (peripheral) | T1 | del | 4/4.5/6 | F | nd | ||
| Lung (central) | T1 | del | 4/4.5/6 | F | nd | ||
| Tonsil (palatine) | — | wt/del | 4.5 | — | nd | ||
| Tonsil (lingual) | T1 | del | 4.5/5/6/7 | F/f | nd | ||
| Submandibular gland | — | — | 4.5/6 | — | nd | ||
| Spleen | — | del | 4.5 | F | nd | ||
| VC 15 | F/67 | Cervical lymph node | T1 | del | 4.5/6 | F | nd |
| Nasopharynx | T1 | wt/del | 4.5 | — | nd | ||
| Larynx | T1 | — | — | F/f | nd | ||
| Oropharynx | — | del | — | — | nd | ||
| Tonsil | T1/T2 | del | 4.5/6 | F | nd | ||
| Parotid gland | T1 | — | 4.5 | — | nd | ||
| Submandibular gland | T1 | — | 4.5 | — | nd | ||
| Cervix | T1 | — | 4.5/6 | F | nd |
| Virus Carrier . | Sex/ Age . | Anatomic Sites . | Types T1/T2 . | LMP1 wt/del . | LMP1 Repeats . | BamHI F/f . | BamHI Z/Z* . |
|---|---|---|---|---|---|---|---|
| VC 1 | F/73 | Mediastinal lymph node | T1 | wt/del | 4.5 | — | — |
| Nasopharynx | T1 | wt/del | 4.5 | F | — | ||
| Larynx | — | wt/del | 5 | — | — | ||
| Anterior tongue | T1 | wt/del | 4 | — | — | ||
| Submandibular gland | T1 | del | 4.5 | — | — | ||
| Peripheral blood | — | wt/del | 5 | F | Z | ||
| VC 2 | F/89 | Mediastinal lymph node | T1 | wt/del | 4.5 | F/f | Z/Z* |
| Nasopharynx | T1 | del | 4.5 | F/f | Z* | ||
| Larynx | T1 | wt/del | 4.5 | — | Z* | ||
| Anterior tongue | T1 | wt/del | 4.5 | F/f | Z/Z* | ||
| Submandibular gland | T1 | wt/del | 4.5 | F/f | Z/Z* | ||
| Peripheral blood | T1 | wt/del | 4.5 | F/f | — | ||
| VC 3 | F/72 | Mediastinal lymph node | — | — | 6 | — | Z/Z* |
| Nasopharynx | T1 | wt/del | 6 | F | Z/Z* | ||
| Larynx | T1 | wt/del | 5/6 | F | Z/Z* | ||
| Anterior tongue | — | wt/del | 5 | — | Z/Z* | ||
| Submandibular gland | T1 | — | 6 | — | Z/Z* | ||
| Peripheral blood | T1 | del | 5 | F | Z/Z* | ||
| VC 4 | M/82 | Mediastinal lymph node | T1/T2 | wt/del | 4.5 | F | Z/Z* |
| Nasopharynx | T1/T2 | wt/del | — | F | Z/Z* | ||
| Larynx | T1/T2 | wt/del | 4.5 | F | Z* | ||
| Anterior tongue | T1/T2 | wt/del | 4.5 | F | Z* | ||
| Submandibular gland | T1/T2 | wt/del | 4.5 | F | Z* | ||
| Peripheral blood | T1/T2 | wt/del | 4.5 | F | Z* | ||
| VC 5 | M/77 | Mediastinal lymph node | T1 | del | 7 | F | — |
| Nasopharynx | T1 | wt/del | 4.5/7 | — | Z/Z* | ||
| Larynx | T1 | wt/del | 4.5/7 | F | Z/Z* | ||
| Anterior tongue | T1 | wt/del | 7 | F | Z/Z* | ||
| Submandibular gland | T1 | wt/del | 4.5/7 | F | Z/Z* | ||
| Peripheral blood | T1 | wt/del | 5/7 | — | Z | ||
| VC 6 | M/68 | Mediastinal lymph node | T1/T2 | wt/del | 4/5 | F | Z/Z* |
| Nasopharynx | T1/T2 | wt/del | 4/5 | F | Z/Z* | ||
| Larynx | T1/T2 | wt/del | 4/5 | F | Z/Z* | ||
| Anterior tongue | nd | nd | nd | nd | nd | ||
| Submandibular gland | T1/T2 | wt/del | 4/5 | F | Z/Z* | ||
| Peripheral blood | T1 | wt/del | 4/5 | F | Z/Z* | ||
| VC 7 | F/83 | Mediastinal lymph node | T1 | del | 7 | F | Z/Z* |
| Nasopharynx | T1/T2 | wt/del | 4.5/7 | F | Z/Z* | ||
| Larynx | T1 | wt/del | 4.5/7 | F | Z/Z* | ||
| Anterior tongue | T2 | wt/del | 7 | F | — | ||
| Submandibular gland | T2 | wt/del | 5/7 | F | Z/Z* | ||
| Peripheral blood | T1/T2 | wt/del | 5/7 | F | Z/Z* | ||
| VC 8 | M/57 | Cervical lymph node | T1 | wt/del | 4/4.5 | F | nd |
| Mediastinal lymph node | T1 | del | 4/4.5 | F | nd | ||
| Para-aortic lymph node | T1 | wt/del | — | F | nd | ||
| Nasopharynx | T1 | del | 4 | F | nd | ||
| Thyroid | T1 | wt/del | 4.5 | — | nd | ||
| Tonsil (palatine) | T1 | wt/del | 4/4.5 | F | nd | ||
| Submandibular gland | T1 | wt/del | 4.5 | — | nd | ||
| Spleen | T1 | wt/del | 4.5 | — | nd | ||
| Thymus | T1 | wt/del | — | — | nd | ||
| VC 9 | F/70 | Cervical lymph node | T1 | wt | 4.5 | F | nd |
| Mediastinal lymph node | T1 | wt | 4.5 | F | nd | ||
| Para-aortic lymph node | — | wt | — | F | nd | ||
| Nasopharynx | T1 | wt | 4.5 | F/f | nd | ||
| Thyroid | — | wt | 4.5 | — | nd | ||
| Tonsil (palatine) | T1 | wt | 4.5 | F | nd | ||
| Submandibular gland | — | wt | 4.5 | — | nd | ||
| Spleen | — | wt | 4.5 | — | nd | ||
| VC 10 | F/26 | Cervical lymph node | T1 | — | 4.5/5 | F/f | nd |
| Mediastinal lymph node | — | — | 4.5 | F/f | nd | ||
| Para-aortic lymph node | T1 | — | 4.5 | — | nd | ||
| Nasopharynx | T1 | — | 4.5/5 | F/f | nd | ||
| Thyroid | T1 | — | 4.5 | — | nd | ||
| Tonsil (palatine) | T1 | wt/del | 4.5/5 | F/f | nd | ||
| Tonsil (lingual) | T1 | wt/del | 4.5 | — | nd | ||
| Lung (central) | T1/T2 | del | 4.5 | — | nd | ||
| Lung (peripheral) | T1 | del | 4.5 | — | nd | ||
| Spleen | T1 | — | 4.5 | — | nd | ||
| Thymus | T1 | — | 4.5 | — | nd | ||
| VC 11 | M/40 | Cervical lymph node | T1 | wt/del | — | — | nd |
| Nasopharynx | T1/T2 | wt/del | 4.5 | F/f | nd | ||
| Larynx | T1 | wt | 4.5/5/6 | — | nd | ||
| Oropharynx | T1 | — | 4.5 | — | nd | ||
| Tonsil | T1 | wt | 4.5 | — | nd | ||
| Parotid gland | — | wt/del | — | F | nd | ||
| Submandibular gland | T1 | del | 4/4.5/5/6 | F | nd | ||
| Penis | T1 | wt | 4.5/5/6 | — | nd | ||
| VC 12 | M/33 | Cervical lymph node | — | wt/del | — | — | nd |
| Nasopharynx | T1 | wt/del | 4.5/5 | F | nd | ||
| Larynx | — | del | — | — | nd | ||
| Oropharynx | — | wt/del | — | — | nd | ||
| Tonsil | — | del | 4.5 | F/f | nd | ||
| Parotid gland | T1 | del | 4.5 | — | nd | ||
| Submandibular gland | T1 | del | 4.5 | — | nd | ||
| Penis | — | del | — | F/f | nd | ||
| VC 13 | M/69 | Cervical lymph node | T1 | wt/del | 4.5 | F/f | nd |
| Nasopharynx | T1 | del | 4/4.5/5/6 | F/f | nd | ||
| Larynx | — | wt/del | — | — | nd | ||
| Oropharynx | — | wt/del | — | — | nd | ||
| Tonsil | T1 | wt/del | 4.5 | F/f | nd | ||
| Parotid gland | T1/T2 | wt/del | 4.5 | F | nd | ||
| Submandibular gland | T1 | wt/del | 4.5 | — | nd | ||
| Penis | T1 | wt/del | 4.5 | — | nd | ||
| VC 14 | M/88 | Cervical lymph node | T1/T2 | del | 4.5/5/6 | F | nd |
| Mediastinal lymph node | T1 | del | 5/6 | F | nd | ||
| Para-aortic lymph node | T1 | del | 5/6 | F | nd | ||
| Thyroid | T1 | del | 4.5 | F | nd | ||
| Lung (peripheral) | T1 | del | 4/4.5/6 | F | nd | ||
| Lung (central) | T1 | del | 4/4.5/6 | F | nd | ||
| Tonsil (palatine) | — | wt/del | 4.5 | — | nd | ||
| Tonsil (lingual) | T1 | del | 4.5/5/6/7 | F/f | nd | ||
| Submandibular gland | — | — | 4.5/6 | — | nd | ||
| Spleen | — | del | 4.5 | F | nd | ||
| VC 15 | F/67 | Cervical lymph node | T1 | del | 4.5/6 | F | nd |
| Nasopharynx | T1 | wt/del | 4.5 | — | nd | ||
| Larynx | T1 | — | — | F/f | nd | ||
| Oropharynx | — | del | — | — | nd | ||
| Tonsil | T1/T2 | del | 4.5/6 | F | nd | ||
| Parotid gland | T1 | — | 4.5 | — | nd | ||
| Submandibular gland | T1 | — | 4.5 | — | nd | ||
| Cervix | T1 | — | 4.5/6 | F | nd |
Peripheral blood was available from VC1-7. Some specific PCR bands are not shown in the figure but were detected in blots of longer exposure, which accounts for the discrepancies between the data summarized in the table and those shown in the figure.
nd indicates PCR assays not performed or insufficient samples for analysis; —, not detected.