The level of GM-CSF in BAL after intranasal delivery of AdGM-CSF or Addl70-3 (pg/ml)*
| . | Day 2 . | Day 4 . | Day 7 . | Day 12 . | Day 19 . |
|---|---|---|---|---|---|
| AdGM-CSF | 1734 ± 433 | 8501 ± 1838 | 3743 ± 1657 | 7.99 ± 0.28 | 12.7 ± 3.4 |
| Addl70-3 | 29.6 | 2.76 | 3.45 | 3.17 | 0 |
| . | Day 2 . | Day 4 . | Day 7 . | Day 12 . | Day 19 . |
|---|---|---|---|---|---|
| AdGM-CSF | 1734 ± 433 | 8501 ± 1838 | 3743 ± 1657 | 7.99 ± 0.28 | 12.7 ± 3.4 |
| Addl70-3 | 29.6 | 2.76 | 3.45 | 3.17 | 0 |
AdGM-CSF = adenoviral gene vector expressing murine GM-CSF; BAL = bronchoalveolar lavage; GM-CSF = granulocyte-macrophage colony-stimulating factor.
BAL samples were collected at various time points after intranasal delivery of AdGM-CSF or Addl70-3. The level of GM-CSF was measured by enzyme-linked immunosorbent assay. The results for AdGM-CSF group are expressed as mean ± SEM from three mice/time point, and mean from two mice/time point for control (Addl70-3) group.