Table 3.

Expression of adhesion molecules in non-Hodgkin lymphomas

REAL Classification L-selectinα4β7CLA αEβ7CD44s References
B-CLL       69, 82, 136, 148, 162, 165, 167, 180-184  
 nodal  +  −  − −  +  
Mantle cell lymphoma       70, 72, 82, 123, 148, 181  
 nodal  +  −  −  −  
 GI-tract (MLP)  +  +  −  −  +  
Marginal zone B-cell lymphoma       70, 82, 124, 148, 181, 186  
 GI-tract (low-grade MALT)  +  +  −  −/+ +  
Follicle center lymphoma       69, 82, 136, 148, 162, 165, 167, 180, 181, 183  
 nodal  +/−  − −  −  +/−  
Diffuse large B-cell lymphoma      69, 70, 82, 102, 136, 148, 162, 164, 165, 167, 169, 180, 181, 183  
 nodal  +/−  −  −  − +/−  
 GI tract  −  −  −  −  
Peripheral T-cell lymphoma       69, 71, 75, 80-82, 125, 127, 130, 148, 183, 185  
 nodal  +  − −  −  +  
 GI tract  −  +/−  − +/−  +  
 skin (MF)  −/+  −  +  −/+  
Anaplastic large cell lymphoma       80, 81, 128  
 nodal  −  −/+  −/+  −  
 skin  −/+  −  +  −/+  nt 
REAL Classification L-selectinα4β7CLA αEβ7CD44s References
B-CLL       69, 82, 136, 148, 162, 165, 167, 180-184  
 nodal  +  −  − −  +  
Mantle cell lymphoma       70, 72, 82, 123, 148, 181  
 nodal  +  −  −  −  
 GI-tract (MLP)  +  +  −  −  +  
Marginal zone B-cell lymphoma       70, 82, 124, 148, 181, 186  
 GI-tract (low-grade MALT)  +  +  −  −/+ +  
Follicle center lymphoma       69, 82, 136, 148, 162, 165, 167, 180, 181, 183  
 nodal  +/−  − −  −  +/−  
Diffuse large B-cell lymphoma      69, 70, 82, 102, 136, 148, 162, 164, 165, 167, 169, 180, 181, 183  
 nodal  +/−  −  −  − +/−  
 GI tract  −  −  −  −  
Peripheral T-cell lymphoma       69, 71, 75, 80-82, 125, 127, 130, 148, 183, 185  
 nodal  +  − −  −  +  
 GI tract  −  +/−  − +/−  +  
 skin (MF)  −/+  −  +  −/+  
Anaplastic large cell lymphoma       80, 81, 128  
 nodal  −  −/+  −/+  −  
 skin  −/+  −  +  −/+  nt 

+ Reported cases all or almost all positive; +/− variable reports, most cases positive; −/+ variable reports, most cases negative; − reported cases negative or sporadically positive. CLL indicates chronic lymphocytic leukemia; GI, gastrointestinal tract; MALT, mucosa-associated lymphoid tissue; MF, mycosis fungoides; MLP, malignant lymphomatous polyposis; nt, not tested.

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