Chemokines involved in lymphocyte migration
| . | Source of Production . | Receptor . | Target Cell(s) . | Reference . |
|---|---|---|---|---|
| CXC-Chemokine | ||||
| IP10 | Monocytes, T cells, keratinocytes, fibroblasts, endothelial cells | CXCR3 | Activated T cells | 40, 172, 173 |
| Mig | Monocytes/macrophages | CXCR3 | Activated T-cells | 40, 172, 174 |
| SDF-1 | Several tissues | CXCR4 | Pro- and pre-B cells, T cells, bone marrow progenitor cells, bone marrow-derived dendritic cells | 175, 176 |
| BLC/BCA-1 | B-cell follicles (secondary lymphoid tissues) | CXCR5 | B cells | 44, 45 |
| CC-Chemokine | ||||
| MIP-3α | Activated monocytes, activated dendritic cells, lymphoid tissues | CCR6 | CD34+ dendritic cells, monocytes, subset of memory T cells | 177, 178 |
| MIP-3β | Dendritic cells, lymphoid tissues | CCR7 | memory T cells, mature dendritic cells | 177, 178 |
| SLC | High endothelial venules (secondary lymphoid tissues) | CCR7 | naive T cells, mature dendritic cells | 43, 179 |
| TARC | Activated endothelium | CCR4 | skin-homing memory T cells | 40a |
| . | Source of Production . | Receptor . | Target Cell(s) . | Reference . |
|---|---|---|---|---|
| CXC-Chemokine | ||||
| IP10 | Monocytes, T cells, keratinocytes, fibroblasts, endothelial cells | CXCR3 | Activated T cells | 40, 172, 173 |
| Mig | Monocytes/macrophages | CXCR3 | Activated T-cells | 40, 172, 174 |
| SDF-1 | Several tissues | CXCR4 | Pro- and pre-B cells, T cells, bone marrow progenitor cells, bone marrow-derived dendritic cells | 175, 176 |
| BLC/BCA-1 | B-cell follicles (secondary lymphoid tissues) | CXCR5 | B cells | 44, 45 |
| CC-Chemokine | ||||
| MIP-3α | Activated monocytes, activated dendritic cells, lymphoid tissues | CCR6 | CD34+ dendritic cells, monocytes, subset of memory T cells | 177, 178 |
| MIP-3β | Dendritic cells, lymphoid tissues | CCR7 | memory T cells, mature dendritic cells | 177, 178 |
| SLC | High endothelial venules (secondary lymphoid tissues) | CCR7 | naive T cells, mature dendritic cells | 43, 179 |
| TARC | Activated endothelium | CCR4 | skin-homing memory T cells | 40a |
Only chemokines discussed in the present paper are listed.