Skin allograft survival in chimeric NOD/Lt mice bearing donor-specific islet allografts
| Bone Marrow Donor . | Islet Allograft Donor . | Skin Allograft Donor . | Skin Allograft Survival (Days) . |
|---|---|---|---|
| C57BL/6 | C57BL/6 | C57BL/6 | >26, >128, >128 |
| C57BL/6 | C57BL/6 | CBA/JCr | 13, 15, 23 |
| Bone Marrow Donor . | Islet Allograft Donor . | Skin Allograft Donor . | Skin Allograft Survival (Days) . |
|---|---|---|---|
| C57BL/6 | C57BL/6 | C57BL/6 | >26, >128, >128 |
| C57BL/6 | C57BL/6 | CBA/JCr | 13, 15, 23 |
Chimeric NOD/Lt mice bearing C57BL/6 islet allografts were selected at random from among those presented in Figure 2 (group 1). They were given either a C57BL/6 (H2b, donor-specific) or a CBA/JCr (H2k, third-party) skin allograft as described in “Materials and Methods.” None of the islet allografts failed in either group during the period of observation.