Number of repopulating cells and mean activity of stem cell (MAS)
| Gestation . | Frequency of CRU (×10−4) . | No of CRU Per Liver . | MAS . | |||
|---|---|---|---|---|---|---|
| Posttransplantation . | Posttransplantation . | Posttransplantation . | ||||
| 4 wk . | 20 wk . | 4 wk . | 20 wk . | 4 wk . | 20 wk . | |
| Day 12 | 1/2.5 | 1/5.0 | 80/liver | 40/liver | 0.16 | 1.25 |
| (1/1.7-1/4.2) | (1/3.1-1/7.7) | |||||
| Day 16 | 1/2.6 | 1/3.9 | 2308/liver | 1538/liver | 0.18 | 1.06 |
| (1/1.6-1/4.1) | (1/2.3-1/6.3) | |||||
| Gestation . | Frequency of CRU (×10−4) . | No of CRU Per Liver . | MAS . | |||
|---|---|---|---|---|---|---|
| Posttransplantation . | Posttransplantation . | Posttransplantation . | ||||
| 4 wk . | 20 wk . | 4 wk . | 20 wk . | 4 wk . | 20 wk . | |
| Day 12 | 1/2.5 | 1/5.0 | 80/liver | 40/liver | 0.16 | 1.25 |
| (1/1.7-1/4.2) | (1/3.1-1/7.7) | |||||
| Day 16 | 1/2.6 | 1/3.9 | 2308/liver | 1538/liver | 0.18 | 1.06 |
| (1/1.6-1/4.1) | (1/2.3-1/6.3) | |||||
The frequencies of competitive repopulating units (CRU) in fetal liver cells at days 12 and 16 of gestation were obtained by limiting dilution analysis as shown in Figure 3 and expressed as mean (95% confidence range). On the basis of the mean frequencies, the total numbers of CRU per liver were calculated. The mean activity of stem cell (MAS) represents the number of RU per CRU.