IgH polymerase chain reaction single cell analysis of MUM1+ and MUM1− cells
| . | IgH-R . | VH Family . | Range of Somatic Mutations (R + S) FW3 and CDR2 . | Coding Capacity . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| VH1 . | VH2 . | VH3 . | VH4 . | VH5 . | VH6 . | VH7 . | ||||
| MUM1+ | ||||||||||
| Germinal center cells | 10/74 | 7 | 3 | 1-11 | ±* | |||||
| Intramantle cells | 5/35 | 3 | 5-8 | + | ||||||
| Intraepithelial plasma cells | 5/62 | 5 | 2-16 | + | ||||||
| MUM1− | ||||||||||
| Mantle cells | 12/82 | 3 | 1 | 0-2 | + | |||||
| . | IgH-R . | VH Family . | Range of Somatic Mutations (R + S) FW3 and CDR2 . | Coding Capacity . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| VH1 . | VH2 . | VH3 . | VH4 . | VH5 . | VH6 . | VH7 . | ||||
| MUM1+ | ||||||||||
| Germinal center cells | 10/74 | 7 | 3 | 1-11 | ±* | |||||
| Intramantle cells | 5/35 | 3 | 5-8 | + | ||||||
| Intraepithelial plasma cells | 5/62 | 5 | 2-16 | + | ||||||
| MUM1− | ||||||||||
| Mantle cells | 12/82 | 3 | 1 | 0-2 | + | |||||
In one cell, the VH rearrangement was out of frame.