Table 1.

MUM1 protein expression in normal lymphohematopoietic tissues

Tissue MUM1 Expression
Tonsil/spleen  
 Germinal center B cells  * 
 Mantle B cells   
 Marginal zone B cells  −  
 Plasma cells  +  
 T cells   
 Macrophages  −  
 Follicular dendritic cells  − 
 Endothelia  −  
 Epithelia  −  
Thymus 
 Cortex  −  
 Medulla  −  
 Hassal corpuscle −  
Bone marrow  
 Erythroid precursors  − 
 Myeloid precursors  −  
 Megakaryocytes  − 
 Osteoblasts  −  
 Osteoclasts  − 
Tissue MUM1 Expression
Tonsil/spleen  
 Germinal center B cells  * 
 Mantle B cells   
 Marginal zone B cells  −  
 Plasma cells  +  
 T cells   
 Macrophages  −  
 Follicular dendritic cells  − 
 Endothelia  −  
 Epithelia  −  
Thymus 
 Cortex  −  
 Medulla  −  
 Hassal corpuscle −  
Bone marrow  
 Erythroid precursors  − 
 Myeloid precursors  −  
 Megakaryocytes  − 
 Osteoblasts  −  
 Osteoclasts  − 
*

A small percentage of strongly MUM1+ cells was present within germinal centers (see “Results”).

Mantle B cells were usually negative but occasionally showed very faint MUM1 expression.

A small percentage (1%-5%) of MUM1+ T cells was present in the GC and the interfollicular area.

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