LTC-IC content of control and anti-TGF-β1 treated (10 μg/mL) CLRPP after 72-hour serum-free cultures
. | CLRPP . | Anti-TGF-β1 CLRPP . |
---|---|---|
LTC-IC frequency* | 1:100 ± 30 | 1:780 ± 100 |
LTC-IC-derived CFU-GM/BFU-E ratio† | 10 ± 2 | 10 ± 3 |
. | CLRPP . | Anti-TGF-β1 CLRPP . |
---|---|---|
LTC-IC frequency* | 1:100 ± 30 | 1:780 ± 100 |
LTC-IC-derived CFU-GM/BFU-E ratio† | 10 ± 2 | 10 ± 3 |
Parallel cultures in the presence of identical doses of irrelevant isotype-matched mouse immunoglobulins showed comparable results to those observed in control CLRPP cultures. Results are presented as the average values ± SD observed in 4 different experiments established with cells collected from 4 different patients.
P < .001.
P > .05.