Outcome of minor histocompatibility antigen-sensitized DLI (mHA-DLI) in mixed chimeric recipients
Dog . | Conditioning (Gy) . | % Donor chimerism before mHA-DLI . | Day of mHA-DLI† . | CD3+ cells infused (×107/kg) . | % Donor chimerism after mHA-DLI* . | ||
---|---|---|---|---|---|---|---|
PBMC . | PBG . | PBMC . | PBG . | ||||
E272 | 1 TBI | 40 | 30 | 651 | 12.0 | 100 | 100 |
E360‡ | 2 TBI | 52 | 64 | 378 | 5.1 | 100 | 100 |
E367 | 1 TBI | 60 | 90 | 490 | 2.4 | 100 | 100 |
E390‡ | 2 TBI | 80 | 82 | 414 | 7.1 | 100 | 100 |
E3992-153 | 4.5 LNI | 5 | 5 | 389 | 6.1 | 100 | 100 |
E400 | 4.5 LNI | 64 | 65 | 503 | 15.0 | 100 | 100 |
E433 | 2 TBI | 70 | 82 | 420 | 8.5 | 98 | 98 |
E501 | 2 TBI | 50 | 54 | 201 | 5.8 | 100 | 100 |
Dog . | Conditioning (Gy) . | % Donor chimerism before mHA-DLI . | Day of mHA-DLI† . | CD3+ cells infused (×107/kg) . | % Donor chimerism after mHA-DLI* . | ||
---|---|---|---|---|---|---|---|
PBMC . | PBG . | PBMC . | PBG . | ||||
E272 | 1 TBI | 40 | 30 | 651 | 12.0 | 100 | 100 |
E360‡ | 2 TBI | 52 | 64 | 378 | 5.1 | 100 | 100 |
E367 | 1 TBI | 60 | 90 | 490 | 2.4 | 100 | 100 |
E390‡ | 2 TBI | 80 | 82 | 414 | 7.1 | 100 | 100 |
E3992-153 | 4.5 LNI | 5 | 5 | 389 | 6.1 | 100 | 100 |
E400 | 4.5 LNI | 64 | 65 | 503 | 15.0 | 100 | 100 |
E433 | 2 TBI | 70 | 82 | 420 | 8.5 | 98 | 98 |
E501 | 2 TBI | 50 | 54 | 201 | 5.8 | 100 | 100 |