Phenotype and EGFP expression of human CB cells engrafting the bone marrow of NOD/SCID mice
Mouse Ref . | Graft Size ×106Cells . | % CD45+ . | % CD45+/EGFP+ . | % CD34+ . | % CD34+/EGFP+ . | % EGFP+ . | |
---|---|---|---|---|---|---|---|
In Total Bone Marrow . | In CD45+Cells . | In CD34+ Cells . | |||||
4M* | 7.1* | 23.4* | 9.2* | 8.3* | 1.7* | 39.5* | 20.0* |
5O | 1.9 | 9.5 | 8.8 | 2.3 | 2.0 | 92.6 | 87.5 |
9B† | 1.9† | 2.7† | 2.4† | 0.6† | 0.3† | 89.0† | 50.1† |
10C | 2.3 | 18.9 | 4.1 | 2.7 | 0.5 | 21.7 | 18.5 |
14B | 3.5 | 79.4 | 11.2 | 14.4 | 1.4 | 14.1 | 9.5 |
15A† | 1.5† | 83.6† | 56.6† | 32.9† | 16.8† | 67.7† | 51.0† |
15B | 1.5 | 83.7 | 33.5 | 13.8 | 5.9 | 40.0 | 43.1 |
16A | 2.8 | 30.5 | 16.7 | 3.4 | 0.9 | 54.8 | 26.5 |
16B | 2.8 | 83.0 | 3.0 | 12.5 | 1.1 | 3.6 | 8.8 |
17B | 2.3 | 66.1 | 5.7 | 10.1 | 0.6 | 8.6 | 6.0 |
Mean ± SE | 2.4 ± 0.2‡ | 53.0 ± 12.2‡ | 11.9 ± 4.0‡ | 8.5 ± 2.1‡ | 1.9 ± 0.7‡ | 33.6 ± 12.0‡ | 28.6 ± 11.0‡ |
Mouse Ref . | Graft Size ×106Cells . | % CD45+ . | % CD45+/EGFP+ . | % CD34+ . | % CD34+/EGFP+ . | % EGFP+ . | |
---|---|---|---|---|---|---|---|
In Total Bone Marrow . | In CD45+Cells . | In CD34+ Cells . | |||||
4M* | 7.1* | 23.4* | 9.2* | 8.3* | 1.7* | 39.5* | 20.0* |
5O | 1.9 | 9.5 | 8.8 | 2.3 | 2.0 | 92.6 | 87.5 |
9B† | 1.9† | 2.7† | 2.4† | 0.6† | 0.3† | 89.0† | 50.1† |
10C | 2.3 | 18.9 | 4.1 | 2.7 | 0.5 | 21.7 | 18.5 |
14B | 3.5 | 79.4 | 11.2 | 14.4 | 1.4 | 14.1 | 9.5 |
15A† | 1.5† | 83.6† | 56.6† | 32.9† | 16.8† | 67.7† | 51.0† |
15B | 1.5 | 83.7 | 33.5 | 13.8 | 5.9 | 40.0 | 43.1 |
16A | 2.8 | 30.5 | 16.7 | 3.4 | 0.9 | 54.8 | 26.5 |
16B | 2.8 | 83.0 | 3.0 | 12.5 | 1.1 | 3.6 | 8.8 |
17B | 2.3 | 66.1 | 5.7 | 10.1 | 0.6 | 8.6 | 6.0 |
Mean ± SE | 2.4 ± 0.2‡ | 53.0 ± 12.2‡ | 11.9 ± 4.0‡ | 8.5 ± 2.1‡ | 1.9 ± 0.7‡ | 33.6 ± 12.0‡ | 28.6 ± 11.0‡ |
Data show analysis of individual recipients at 90 to 120 days after transplantation except for
(20 days) and for
(40 days).
Only data corresponding to 90 to 120 days after transplantation are considered for determinations of mean values. Numbers in the code of each recipient correspond to the origin of the cord blood graft in Table 1.