Sensitivity of quality-adjusted life years for intention to transplant versus intention to transfuse to changes in quality of life estimates for disease and treatment states
| Disease/ treatment state . | Baseline quality of life . | Range . | Intention to transplant (QALYs range) . | Intention to transfuse (QALYs range) . |
|---|---|---|---|---|
| BMT success | 0.95 | 0.0 to 1.0 | 14.1-15.3 | 14.9-14.9 |
| BMT cGVHD | 0.85 | 0.0 to 1.0 | 15.0-15.3 | 14.9-14.9 |
| BMT rejection | 0.70 | 0.0 to 1.0 | 15.2-15.3 | 14.9-14.9 |
| PBT success | 0.85 | 0.0 to 1.0 | 11.7-15.9 | 11.1-15.6 |
| PBT alloimmunized | 0.80 | 0.0 to 1.0 | 15.0-15.3 | 14.7-15.0 |
| PBT noncompliant with transfusion regimen | 0.85 | 0.0 to 1.0 | 13.6-15.5 | 13.2-15.3 |
| PBT noncompliant with iron chelation | 0.75 | 0.0 to 1.0 | 10.4-16.8 | 9.7-16.7 |
| Refusal of BMT and PBT | 0.80 | 0.0 to 1.0 | 13.9-15.6 | 13.5-15.3 |
| Hemorrhagic stroke | 0.45 | 0.0 to 1.0 | 15.0-15.5 | 14.8-15.2 |
| Ischemic stroke | 0.45 | 0.0 to 1.0 | 13.1-17.9 | 12.7-17.7 |
| Disease/ treatment state . | Baseline quality of life . | Range . | Intention to transplant (QALYs range) . | Intention to transfuse (QALYs range) . |
|---|---|---|---|---|
| BMT success | 0.95 | 0.0 to 1.0 | 14.1-15.3 | 14.9-14.9 |
| BMT cGVHD | 0.85 | 0.0 to 1.0 | 15.0-15.3 | 14.9-14.9 |
| BMT rejection | 0.70 | 0.0 to 1.0 | 15.2-15.3 | 14.9-14.9 |
| PBT success | 0.85 | 0.0 to 1.0 | 11.7-15.9 | 11.1-15.6 |
| PBT alloimmunized | 0.80 | 0.0 to 1.0 | 15.0-15.3 | 14.7-15.0 |
| PBT noncompliant with transfusion regimen | 0.85 | 0.0 to 1.0 | 13.6-15.5 | 13.2-15.3 |
| PBT noncompliant with iron chelation | 0.75 | 0.0 to 1.0 | 10.4-16.8 | 9.7-16.7 |
| Refusal of BMT and PBT | 0.80 | 0.0 to 1.0 | 13.9-15.6 | 13.5-15.3 |
| Hemorrhagic stroke | 0.45 | 0.0 to 1.0 | 15.0-15.5 | 14.8-15.2 |
| Ischemic stroke | 0.45 | 0.0 to 1.0 | 13.1-17.9 | 12.7-17.7 |
Abbreviations are explained in Table 6.