Table 1.

Outcomes of patients with sickle cell undergoing bone marrow transplantation

Investigator Site Total patients Median follow-up (mo) Deaths N (%) cGVHD N (%)Rejection N (%)
Walters et al10 Multi-center  32  26.5  2 (6.3%)  4 (12.5%) 4 (12.5%)  
Abboud et al11 South Carolina  27.2  1 (11.1%)  1 (11.1%)  0 (0%)  
Vermylen et al12 Belgium  50  60.0  2 (4.0%) 10 (20.0%)  5 (10%)  
Bernaudin  et al13 France  26  54.5  2 (7.7%)  4 (15.4%) 5 (19.2%)  
Total   117  47.1* 7 (6.0%) 19 (16.2%)  14 (12.0%) 
Investigator Site Total patients Median follow-up (mo) Deaths N (%) cGVHD N (%)Rejection N (%)
Walters et al10 Multi-center  32  26.5  2 (6.3%)  4 (12.5%) 4 (12.5%)  
Abboud et al11 South Carolina  27.2  1 (11.1%)  1 (11.1%)  0 (0%)  
Vermylen et al12 Belgium  50  60.0  2 (4.0%) 10 (20.0%)  5 (10%)  
Bernaudin  et al13 France  26  54.5  2 (7.7%)  4 (15.4%) 5 (19.2%)  
Total   117  47.1* 7 (6.0%) 19 (16.2%)  14 (12.0%) 

cGVHD = chronic graft versus host disease.

*

Total median follow-up time was calculated as a weighted average of the median follow-up times from the 4 studies.

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