Table 6. Distribution of potential... | American Society of Hematology

Table 6.

Distribution of potential glutathione S-transferase low-risk genotypes and their association with the occurrence of relapse in 64 case subjects and 64 successfully treated matched control subjects with acute lymphoblastic leukemia from ALL-BFM trials 86 and 90

	No. of Subjects and Prevalence (%)		OR (95% CI)	P Value
	Cases	Controls	OR (95% CI)	P Value
Genotype combinations
—No low risk genotype^6-150	33 (51.6)	20 (31.3)	1.00^6-151
—1 low risk genotype	27 (42.2)	28 (43.8)	0.53 (0.24-1.19)	0.123
—2 or 3 low risk genotypes	4 (6.3)	16 (25.0)	0.29 (0.06-1.37)	0.118

	No. of Subjects and Prevalence (%)		OR (95% CI)	P Value
	Cases	Controls	OR (95% CI)	P Value
Genotype combinations
—No low risk genotype^6-150	33 (51.6)	20 (31.3)	1.00^6-151
—1 low risk genotype	27 (42.2)	28 (43.8)	0.53 (0.24-1.19)	0.123
—2 or 3 low risk genotypes	4 (6.3)	16 (25.0)	0.29 (0.06-1.37)	0.118

F6-150

Low-risk genotypes: GSTM1 null, GSTT1 null, andGSTP1 Val₁₀₅/Val₁₀₅ (corresponding toGSTP1 haplotypes GSTP1*B/GSTP1*B, orGSTP1*B/GSTO1*C).

F6-151

Reference category.

OR: Odds ratio; CI: confidence interval.

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