Table 3.

Survival, according to risk factors, in all patients and in patients with primary MDS

Risk Factor All Patients (n = 50) Patients with Primary MDS (n = 42)
Patients Surviving/ Total No. of Patients KM Estimate of RFS at 3 y Patients Surviving/ Total No. of Patients at Risk KM Estimate of RFS at 3 y
Source of stem cells  
 HLA-identical sibling  17/36  0.39 16/30  0.47  
 HLA-nonidentical relative  0/4  0.00 0/3  0.00  
 Syngeneic donor  2/4  0.673-150 2/3 1.003-150 
 Unrelated donor  3/6  0.50  3/6  0.50 
Etiology of MDS  
 Primary  21/42  0.38  — —  
 Secondary  1/8  0.13  — —  
FAB classification  
 RA  7/13  0.53 7/12  0.57  
 RAEB  9/19  0.46  9/17  0.52 
 RAEB-T/AML  6/16  0.383-150 5/11  0.453-150 
 CMML 0/2  0.00  0/2  0.00  
Cytogenetic risk3-151 
 Low 13/24  0.45  12/22  0.50  
 Intermediate  5/7 0.71  5/6  0.83  
 High  3/15  0.213-150 3/11 0.303-150 
IPSS3-152 
 Low (0)  1/2  0.50  1/1  1.00 
 Intermediate 1 (0.5-1)  7/14  0.50  7/13  0.54 
 Intermediate 2 (1.5-2.0)  10/19  0.41  10/18  0.44 
 High (>2.5)  3/10  0.273-150 2/6  0.503-150 
Risk Factor All Patients (n = 50) Patients with Primary MDS (n = 42)
Patients Surviving/ Total No. of Patients KM Estimate of RFS at 3 y Patients Surviving/ Total No. of Patients at Risk KM Estimate of RFS at 3 y
Source of stem cells  
 HLA-identical sibling  17/36  0.39 16/30  0.47  
 HLA-nonidentical relative  0/4  0.00 0/3  0.00  
 Syngeneic donor  2/4  0.673-150 2/3 1.003-150 
 Unrelated donor  3/6  0.50  3/6  0.50 
Etiology of MDS  
 Primary  21/42  0.38  — —  
 Secondary  1/8  0.13  — —  
FAB classification  
 RA  7/13  0.53 7/12  0.57  
 RAEB  9/19  0.46  9/17  0.52 
 RAEB-T/AML  6/16  0.383-150 5/11  0.453-150 
 CMML 0/2  0.00  0/2  0.00  
Cytogenetic risk3-151 
 Low 13/24  0.45  12/22  0.50  
 Intermediate  5/7 0.71  5/6  0.83  
 High  3/15  0.213-150 3/11 0.303-150 
IPSS3-152 
 Low (0)  1/2  0.50  1/1  1.00 
 Intermediate 1 (0.5-1)  7/14  0.50  7/13  0.54 
 Intermediate 2 (1.5-2.0)  10/19  0.41  10/18  0.44 
 High (>2.5)  3/10  0.273-150 2/6  0.503-150 

RFS denotes relapse-free survival; IPSS, International Prognostic Scoring System.

F3-150

One patient died 3.1 years after transplantation.

F3-151

Not available in 4 patients.

F3-152

Variables incomplete in 5 patients.

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