VH gene family use in diffuse large B-cell lymphoma
VH Family . | DLBCLPresent Study (%) (n = 58) . | Relative VH Family Size (%)2 . | PBL-EBV Lines (%) (n = 97)31 . | Adult PBL (in situ hybridization) (%)32 . | Adult PBL (single-cell PCR) (%)33 . | Adult PBL (PCR) (%)34 . |
---|---|---|---|---|---|---|
VH1 | 12.1 | 18.8 | 13 | 11 | 12.7 | 13 |
VH2 | 10.3 | 6.3 | 1 | 3 | 4.2 | 1 |
VH3 | 44.8 | 45.8 | 57 | 52 | 56.3 | 55 |
VH4 | 25.9 | 20.8 | 19 | 19 | 19.7 | 26 |
VH5 | 5.2 | 4.2 | 5 | 10 | 5.6 | 3 |
VH6 | 0 | 2.1 | 2 | 5 | 1.4 | 1 |
VH7 | 1.7 | 2.1 | 0 | 0 | 0 | 0 |
VH Family . | DLBCLPresent Study (%) (n = 58) . | Relative VH Family Size (%)2 . | PBL-EBV Lines (%) (n = 97)31 . | Adult PBL (in situ hybridization) (%)32 . | Adult PBL (single-cell PCR) (%)33 . | Adult PBL (PCR) (%)34 . |
---|---|---|---|---|---|---|
VH1 | 12.1 | 18.8 | 13 | 11 | 12.7 | 13 |
VH2 | 10.3 | 6.3 | 1 | 3 | 4.2 | 1 |
VH3 | 44.8 | 45.8 | 57 | 52 | 56.3 | 55 |
VH4 | 25.9 | 20.8 | 19 | 19 | 19.7 | 26 |
VH5 | 5.2 | 4.2 | 5 | 10 | 5.6 | 3 |
VH6 | 0 | 2.1 | 2 | 5 | 1.4 | 1 |
VH7 | 1.7 | 2.1 | 0 | 0 | 0 | 0 |
EBV indicates Epstein-Barr virus; PBL, peripheral blood lymphocyte; PCR, polymerase chain reaction.