Genotype distribution of 2 integrin Bgl II polymorphism in patients with type II diabetes and in normal subjects
| . | n . | Bgl II (+/+)/Bgl II (+/−) n (%)/n (%) . | Bgl II (−/−) n (%) . | P Value* and Odds Ratio* (OR) . |
|---|---|---|---|---|
| All patients | ||||
| Without retinopathy or nephropathy (group A) | 108 | 13 (12.0)/47 (43.6) | 48 (44.4) | |
| .0270 (OR = 1.84) | ||||
| With retinopathy (group B + C) | 119 | 24 (20.2)/59 (49.5) | 36 (30.3) | |
| .0242 (OR = 2.00) | ||||
| Without nephropathy (group A + B) | 143 | 21 (14.7)/62 (43.3) | 60 (42.0) | |
| .0437 (OR = 1.81) | ||||
| With nephropathy (group C) | 84 | 16 (19.0)/44 (52.4) | 24 (28.6) | |
| Disease duration ≥10 y | ||||
| Without retinopathy or nephropathy (group A) | 107 | 12 (11.2)/47 (43.9) | ||
| 48 (44.9) | ||||
| With retinopathy (group B + C) | 98 | 23 (23.5)/48 (48.9) | .0102 (OR = 2.14) | |
| 27 (27.6) | ||||
| .0120 (OR = 2.31) | ||||
| Without nephropathy (group A + B) | 136 | 20 (14.7)/59 (43.4) | 57 (41.9) | |
| .0262 (OR = 2.04) | ||||
| With nephropathy (group C) | 69 | 15 (21.7)/36 (52.2) | 18 (26.1) | |
| Normal subjects | 169 | 30 (17.8)/81 (47.9) | 58 (34.3) |
| . | n . | Bgl II (+/+)/Bgl II (+/−) n (%)/n (%) . | Bgl II (−/−) n (%) . | P Value* and Odds Ratio* (OR) . |
|---|---|---|---|---|
| All patients | ||||
| Without retinopathy or nephropathy (group A) | 108 | 13 (12.0)/47 (43.6) | 48 (44.4) | |
| .0270 (OR = 1.84) | ||||
| With retinopathy (group B + C) | 119 | 24 (20.2)/59 (49.5) | 36 (30.3) | |
| .0242 (OR = 2.00) | ||||
| Without nephropathy (group A + B) | 143 | 21 (14.7)/62 (43.3) | 60 (42.0) | |
| .0437 (OR = 1.81) | ||||
| With nephropathy (group C) | 84 | 16 (19.0)/44 (52.4) | 24 (28.6) | |
| Disease duration ≥10 y | ||||
| Without retinopathy or nephropathy (group A) | 107 | 12 (11.2)/47 (43.9) | ||
| 48 (44.9) | ||||
| With retinopathy (group B + C) | 98 | 23 (23.5)/48 (48.9) | .0102 (OR = 2.14) | |
| 27 (27.6) | ||||
| .0120 (OR = 2.31) | ||||
| Without nephropathy (group A + B) | 136 | 20 (14.7)/59 (43.4) | 57 (41.9) | |
| .0262 (OR = 2.04) | ||||
| With nephropathy (group C) | 69 | 15 (21.7)/36 (52.2) | 18 (26.1) | |
| Normal subjects | 169 | 30 (17.8)/81 (47.9) | 58 (34.3) |
Bgl II (+/+) + Bgl II (+/−) versus Bgl II (−/−).