Production of p24 Ag by SK-specific and Der p 1–specific short-term T cell lines infected in vitro with the HIV-1BaL strain
| Ag Specificity . | No. of T Cell Lines . | p24 Ag (pg/mL) . | |
|---|---|---|---|
| HIV-1IIIB* . | HIV-1BaL . | ||
| SK | 8 | 100 ± 17 | 1,460 ± 210 |
| Der p 1 | 8 | 783 ± 120 | 4,234 ± 635 |
| Pvalues | <.005 | <.005 | |
| Ag Specificity . | No. of T Cell Lines . | p24 Ag (pg/mL) . | |
|---|---|---|---|
| HIV-1IIIB* . | HIV-1BaL . | ||
| SK | 8 | 100 ± 17 | 1,460 ± 210 |
| Der p 1 | 8 | 783 ± 120 | 4,234 ± 635 |
| Pvalues | <.005 | <.005 | |
SK-specific and Der p 1–specific short-term T cell lines were generated from PBMC of 8 Der p 1–sensitive atopic donors, as described in Materials and Methods. On day 15, T cell lines were infected with the HIV-1IIIB or HIV-1BaL strains, and on day 6 after infection, they were assessed for p24 Ag production, as previously described.
Values represent the mean ± SEM (standard error of the mean) of p24 Ag concentrations in cell-free supernatants.