Table 1. Characterization of BCR/ABL... | American Society of Hematology

Table 1.

Characterization ofBCR/ABL^tg/−p53^+/− leukemic mice

Mouse No.	Sex/ Age at Diagnosis, mo	Macroscopic Tumor Sites	Surface Markers	DNA Status (TCR probe)	p210^bcr/abl Expression	p53 Gene Status
1	F/8.0	Thymus, PE, Spleen	Thy1.2⁺, CD4⁻, CD8⁻	G/R	Yes	G/T
2	M/2.8	Thymus, PE	Thy1.2⁺, CD4⁺, CD8⁺	G/R	Yes	Loss/T
3	F/11.5	Thymus, PE, Spleen	ND	ND	Yes	G/T
4	M/9.7	Thymus, PE	Thy1.2⁺, CD4⁺, CD8⁺	G/R	Yes	G/T
5	F/3.0	Thymus	Thy1.2⁺, CD4⁺, CD8⁺	G/R	Yes	Loss/T
6	F/3.2	Thymus	Thy1.2⁺, CD4⁺, CD8⁺	G/R	Yes	Loss/T
7	M/4.0	Thymus	Thy1.2⁺, CD4⁻, CD8⁺	G/R	Yes	Loss/T
8	M/2.3	Thymus, PE	Thy1.2⁺, CD4⁺, CD8⁻	G/R	Yes	Loss/T
9	M/4.1	Thymus	ND	ND	Yes	Loss/T

Mouse No.	Sex/ Age at Diagnosis, mo	Macroscopic Tumor Sites	Surface Markers	DNA Status (TCR probe)	p210^bcr/abl Expression	p53 Gene Status
1	F/8.0	Thymus, PE, Spleen	Thy1.2⁺, CD4⁻, CD8⁻	G/R	Yes	G/T
2	M/2.8	Thymus, PE	Thy1.2⁺, CD4⁺, CD8⁺	G/R	Yes	Loss/T
3	F/11.5	Thymus, PE, Spleen	ND	ND	Yes	G/T
4	M/9.7	Thymus, PE	Thy1.2⁺, CD4⁺, CD8⁺	G/R	Yes	G/T
5	F/3.0	Thymus	Thy1.2⁺, CD4⁺, CD8⁺	G/R	Yes	Loss/T
6	F/3.2	Thymus	Thy1.2⁺, CD4⁺, CD8⁺	G/R	Yes	Loss/T
7	M/4.0	Thymus	Thy1.2⁺, CD4⁻, CD8⁺	G/R	Yes	Loss/T
8	M/2.3	Thymus, PE	Thy1.2⁺, CD4⁺, CD8⁻	G/R	Yes	Loss/T
9	M/4.1	Thymus	ND	ND	Yes	Loss/T

PE indicates pleural effusion; G/R, germline/rearranged; G/T, germline/targeted; and ND, not done.