Frequency of HFE genotypes in PCT patients and controls
| Genotype . | PCT n = 87 . | Control n = 56 . | P Value . |
|---|---|---|---|
| Cys282Tyr/Cys282Tyr | 17 (19%) | 0 | .0001 |
| Cys282Tyr/WT | 13 (15%) | 7 (13%) | .8061 |
| Cys282Tyr/His63Asp | 6 (7%) | 0 | .0447 |
| His63Asp/His63Asp | 6 (7%) | 1 (2%) | .2460 |
| His63Asp/WT | 13 (15%) | 10 (18%) | .6480 |
| WT/WT | 32 (37%) | 38 (68%) | .0003 |
| Genotype . | PCT n = 87 . | Control n = 56 . | P Value . |
|---|---|---|---|
| Cys282Tyr/Cys282Tyr | 17 (19%) | 0 | .0001 |
| Cys282Tyr/WT | 13 (15%) | 7 (13%) | .8061 |
| Cys282Tyr/His63Asp | 6 (7%) | 0 | .0447 |
| His63Asp/His63Asp | 6 (7%) | 1 (2%) | .2460 |
| His63Asp/WT | 13 (15%) | 10 (18%) | .6480 |
| WT/WT | 32 (37%) | 38 (68%) | .0003 |
Controls were members of the Utah hemochromatosis pedigrees, who shared no HLA haplotypes with the pedigree proband.20 P values were calculated with the Fisher exact test. WT indicates wild type.