The iron phenotype of 99 patients with PCT and 99 controls
| . | Male . | Female . | ||||
|---|---|---|---|---|---|---|
| PCT . | Control . | P Value . | PCT . | Control . | P Value . | |
| Serum iron (μmol/L) | 26.0 ± 1.8 | 19.3 ± 0.72 | .0030 | 23.3 ± 1.8 | 16.5 ± 1.25 | .0046 |
| Transferrin saturation (%) | 44 ± 3 | 30 ± 1 | .0003 | 46 ± 4 | 26 ± 2 | .0010 |
| Serum Ferritin (μg/L) | 472 ± 42 | 88 ± 8 | .0001 | 498 ± 107 | 49 ± 9 | .0001 |
| (399) | (70) | (240) | (24) | |||
| . | Male . | Female . | ||||
|---|---|---|---|---|---|---|
| PCT . | Control . | P Value . | PCT . | Control . | P Value . | |
| Serum iron (μmol/L) | 26.0 ± 1.8 | 19.3 ± 0.72 | .0030 | 23.3 ± 1.8 | 16.5 ± 1.25 | .0046 |
| Transferrin saturation (%) | 44 ± 3 | 30 ± 1 | .0003 | 46 ± 4 | 26 ± 2 | .0010 |
| Serum Ferritin (μg/L) | 472 ± 42 | 88 ± 8 | .0001 | 498 ± 107 | 49 ± 9 | .0001 |
| (399) | (70) | (240) | (24) | |||
Of the 99 patients studied, 65 were males, and 34 were females. The 65 male and 34 female controls were matched by sex and age (±5 years) with PCT patients. Controls represented members of hemochromatosis pedigrees who shared no HLA alloantigen with the hemochromatosis homozygote pedigree proband.19 Pvalues (two-tailed) were calculated with the paired two sample Wilcoxon signed rank test. Values are expressed as the mean ± SEM (standard error of the mean). Values in parentheses represent the median value.