PMLRARm4 leukemias blood
| Mice . | WBC . | HGB . | PLT . | Lymph . | Blast + Pro . | Imm Neut . | Mat Neut . | Mono . | Eosin . |
|---|---|---|---|---|---|---|---|---|---|
| Control | 3.0 ± 2.1 | 13.6 ± 0.3 | 1064 ± 69 | 89.9 ± 5.4 | 0 | 0 | 7.9 ± 3.9 | 1.7 ± 2.0 | 0.4 ± 0.2 |
| PR | 4.5 ± 5.0 | 7.8 ± 1.8 | 334 ± 69 | 87.2 ± 7.2 | 6.8 ± 4.7 | 3.2 ± 2.2 | 2.0 ± 1.5 | 0.5 ± 0.8 | 0.3 ± 0.8 |
| PRm4 | 67.7 ± 50.7 | 7.8 ± 1.2 | 483 ± 192 | 48.8 ± 25.3 | 16.9 ± 14.0 | 13.9 ± 10.5 | 17.6 ± 19.1 | 2.4 ± 3.5 | 0.3 ± 0.5 |
| Leukemia | |||||||||
| 4042 | 101.33-150 | 8.73-150 | 6313-150 | 52 | 11 | 11 | 17 | 8 | 1 |
| 4048.2 | 3.73-150 | 93-150 | 3173-150 | 88 | 8 | 3 | 1 | 0 | 0 |
| 4048.3 | Not increased | NA | NA | 23 | 9 | 20 | 47 | 0 | 1 |
| 4048.5 | 6.6 | 7.7 | 389 | 61 | 13.5 | 16.5 | 3.5 | 5.5 | 0 |
| 4099 | 1413-150 | 7.43-150 | 7423-150 | 49 | 45 | 3 | 3 | 0 | 0 |
| 4104 | 86.1 | 6.1 | 335 | 20 | 15 | 30 | 34 | 1 | 0 |
| Mice . | WBC . | HGB . | PLT . | Lymph . | Blast + Pro . | Imm Neut . | Mat Neut . | Mono . | Eosin . |
|---|---|---|---|---|---|---|---|---|---|
| Control | 3.0 ± 2.1 | 13.6 ± 0.3 | 1064 ± 69 | 89.9 ± 5.4 | 0 | 0 | 7.9 ± 3.9 | 1.7 ± 2.0 | 0.4 ± 0.2 |
| PR | 4.5 ± 5.0 | 7.8 ± 1.8 | 334 ± 69 | 87.2 ± 7.2 | 6.8 ± 4.7 | 3.2 ± 2.2 | 2.0 ± 1.5 | 0.5 ± 0.8 | 0.3 ± 0.8 |
| PRm4 | 67.7 ± 50.7 | 7.8 ± 1.2 | 483 ± 192 | 48.8 ± 25.3 | 16.9 ± 14.0 | 13.9 ± 10.5 | 17.6 ± 19.1 | 2.4 ± 3.5 | 0.3 ± 0.5 |
| Leukemia | |||||||||
| 4042 | 101.33-150 | 8.73-150 | 6313-150 | 52 | 11 | 11 | 17 | 8 | 1 |
| 4048.2 | 3.73-150 | 93-150 | 3173-150 | 88 | 8 | 3 | 1 | 0 | 0 |
| 4048.3 | Not increased | NA | NA | 23 | 9 | 20 | 47 | 0 | 1 |
| 4048.5 | 6.6 | 7.7 | 389 | 61 | 13.5 | 16.5 | 3.5 | 5.5 | 0 |
| 4099 | 1413-150 | 7.43-150 | 7423-150 | 49 | 45 | 3 | 3 | 0 | 0 |
| 4104 | 86.1 | 6.1 | 335 | 20 | 15 | 30 | 34 | 1 | 0 |
Data are shown as arithmetic means ± SD. WBC: White blood cell count in 1000/μL. HGB: Hemoglobin in gms/dL. PLT: Platelet Count in 1000/μL. Percentages of nucleated leukocytes were derived from 200 cell differential counts of Wright's Giemsa stained blood smears. Lymph: lymphocytes. Blast + Pro: blasts & promyelocytes. Imm Neut: neutrophilic myelocytes & metamyelocytes. Mat Neut: neutrophilic band, mature ring, & polymorphonuclear forms. Mono: monocytes. Eosin: eosinophils. WBC, HGB, and PLT: Control n = 7, PR (MRP8-PMLRARα) primary leukemias n = 10, PRm4 (MRP8-PMLRARαm4) n = 5 (leukemic mice 4104 & 4048.5 and transplant recipients of leukemias 4042, 4048.2, and 4099). Differential counts: Control n = 7, PR primary leukemias n = 6, PRm4 primary leukemias n = 6.
WBC, HGB, PLT obtained on initial transplant recipients. Peripheral blood was not obtained from leukemic mouse 4048.4. NA: not available.