Table 2.

Clinico-pathologic correlation of Hodgkin's disease cases with versus cases without tissue eosinophilia

Factors No Eosinophilia Eosinophilia
Age 
 <20  10%  9%  
 20-30  32% 40%  
 30-40  27%  25%  
 40-50 14%  12%  
 50-60  12% 9%  
 >60  5%  5% 
Gender  
 Male  54%  59%  
 Female 46%  41%  
Histology  
 LP/NS1/LRC 69%  56%  
 NS2/MC/LD  31% 44%  
Stage  
 I  14%  11% 
 II  40%  46%  
 III  30% 29%  
 IV  16%  14% 
B-symptoms  
 Yes  39%  42% 
Karnofsky Index  
 9-10  90%  89% 
 <9  10%  11%  
Large mediastinal mass 18%  21%  
Extranodal spread  23% 23%  
High ESR  43%  53%  
>3 nodes areas involved  56%  60%  
Hemoglobine (Hb)  
 <12 (m)/<10.5 (f)  16%  14% 
Serum albumin  
 <4 g/dL  35%  37% 
Lactate dehydrogenase (LDH)  
 >400 U  2.9%  2.3% 
Alkaline phosphatase (AP)  
 >230 U  14% 15%  
Lymphocytes as % of white blood cells 
 <10%  21%  26% 
Factors No Eosinophilia Eosinophilia
Age 
 <20  10%  9%  
 20-30  32% 40%  
 30-40  27%  25%  
 40-50 14%  12%  
 50-60  12% 9%  
 >60  5%  5% 
Gender  
 Male  54%  59%  
 Female 46%  41%  
Histology  
 LP/NS1/LRC 69%  56%  
 NS2/MC/LD  31% 44%  
Stage  
 I  14%  11% 
 II  40%  46%  
 III  30% 29%  
 IV  16%  14% 
B-symptoms  
 Yes  39%  42% 
Karnofsky Index  
 9-10  90%  89% 
 <9  10%  11%  
Large mediastinal mass 18%  21%  
Extranodal spread  23% 23%  
High ESR  43%  53%  
>3 nodes areas involved  56%  60%  
Hemoglobine (Hb)  
 <12 (m)/<10.5 (f)  16%  14% 
Serum albumin  
 <4 g/dL  35%  37% 
Lactate dehydrogenase (LDH)  
 >400 U  2.9%  2.3% 
Alkaline phosphatase (AP)  
 >230 U  14% 15%  
Lymphocytes as % of white blood cells 
 <10%  21%  26% 

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