Donor cell reconstitution per 105 cells injected after 7 days of culture with or without 1 μmol ATRA
| Experiment Number . | Median Values for % Donor per 105 Cells Injected . | P-value . | |
|---|---|---|---|
| No ATRA . | ATRA . | ||
| 1 | 2.55 | 3.62 | 0.33 |
| 2 | 1.11 | 7.17 | 0.002 |
| 3 | 0.47 | 2.13 | 0.02 |
| Average of all 3 experiments | 0.78 | 4.09 | < 0.001 |
| Experiment Number . | Median Values for % Donor per 105 Cells Injected . | P-value . | |
|---|---|---|---|
| No ATRA . | ATRA . | ||
| 1 | 2.55 | 3.62 | 0.33 |
| 2 | 1.11 | 7.17 | 0.002 |
| 3 | 0.47 | 2.13 | 0.02 |
| Average of all 3 experiments | 0.78 | 4.09 | < 0.001 |
The indicated median values represent the median value of the percentage of donor cells in each mouse adjusted per 105cultured cells injected per treatment group after 7 days of culture with or without 1 μmol ATRA. Data were analyzed by the Wilcoxon rank-sum test, and the P-values are given for each experiment. To average the results of all 3 experiments and account for variability between transplants, the data were further analyzed by fitting a regression model on the ranks of the data, with treatment group (ATRA vs No ATRA) being the explanatory variable of interest and experiment number included as an additional explanatory variable.