Table 2.

BLR1/CXCR5 expression in B-cell tumors and the non-neoplastic T cells in these patients

Tumor Type Cases Tested %-Positive B Cells (CD19-positive) %-Positive Non-Neoplastic T Cells (CD3-positive)
L1 or L2 ALL  8/8  95  74  
Burkitt's lymphoma/L3 ALL  1/1  91  69  
CLL  13/13  100  57 
Prolymphocytic leukemia  1/1  99  17  
Hairy cell leukemia  1/1  100  28  
Mantle cell lymphoma  1/1  66 34  
Follicular lymphoma  2/2  100  98  
Marginal zone lymphoma  2/2  85  35  
Lymphoplasmacytic lymphoma  1/1 91  74  
Reactive lymph node  1/1  90  83 
Peripheral blood  8/8  91  15 
Tumor Type Cases Tested %-Positive B Cells (CD19-positive) %-Positive Non-Neoplastic T Cells (CD3-positive)
L1 or L2 ALL  8/8  95  74  
Burkitt's lymphoma/L3 ALL  1/1  91  69  
CLL  13/13  100  57 
Prolymphocytic leukemia  1/1  99  17  
Hairy cell leukemia  1/1  100  28  
Mantle cell lymphoma  1/1  66 34  
Follicular lymphoma  2/2  100  98  
Marginal zone lymphoma  2/2  85  35  
Lymphoplasmacytic lymphoma  1/1 91  74  
Reactive lymph node  1/1  90  83 
Peripheral blood  8/8  91  15 

Flow cytometric detection using 51505.111 CXCR5 monoclonal antibody with gating on the lymphocyte population by forward and side scatter properties.

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