Table 1. Clinical data of 8 patients... | American Society of Hematology

Table 1.

Clinical data of 8 patients with CHS

Patient	Age at Diagnosis Current Age (y)	Accelerated Phases			BMT	Consanguinity Family History	Neurologic Manifestations
Patient	Age at Diagnosis Current Age (y)	Age at Onset	Severity	Suspected Triggering Factor	BMT	Consanguinity Family History	Neurologic Manifestations
1	5.5	5.5	++	EBV	+	−	−
	6.0^*					−
2	2.5	2.5	+	EBV	+	+	Low intellectual capacity (QD = 80)
	22					+
3	14	14	++	?	−	+	Mental retardation
	16					−
4	1	1.6	++	EBV	+	+	Poor performance at school
	14^*	14^†				−
5	1.3	1.3	++	EBV	−	−
	1.5^*					+	−
6	7.8	0	−	−	−	−
	10					+	−
7	<1	2	++	EBV	−	+	Low intellectual capacity (QD = 75)
	11					+
8	<1	1	++	?	+	+
	1.4^*					+	−

Patient	Age at Diagnosis Current Age (y)	Accelerated Phases			BMT	Consanguinity Family History	Neurologic Manifestations
Patient	Age at Diagnosis Current Age (y)	Age at Onset	Severity	Suspected Triggering Factor	BMT	Consanguinity Family History	Neurologic Manifestations
1	5.5	5.5	++	EBV	+	−	−
	6.0^*					−
2	2.5	2.5	+	EBV	+	+	Low intellectual capacity (QD = 80)
	22					+
3	14	14	++	?	−	+	Mental retardation
	16					−
4	1	1.6	++	EBV	+	+	Poor performance at school
	14^*	14^†				−
5	1.3	1.3	++	EBV	−	−
	1.5^*					+	−
6	7.8	0	−	−	−	−
	10					+	−
7	<1	2	++	EBV	−	+	Low intellectual capacity (QD = 75)
	11					+
8	<1	1	++	?	+	+
	1.4^*					+	−

Died.

Relapse after bone marrow graft rejection.

Patients 5 and 6 are siblings.

BMT, bone marrow transplantation; CHS, Chediak–Higashi syndrome; EBV, Epstein–Barr virus.