Transduction frequencies of human cell subsets and CFC from engrafted NOD/SCID mice
| Mouse . | Cells Injected (×105) . | % Human Cells . | % Human Cells EGFP+ . | % Human Myeloid Cells EGFP+ . | % Human Lymphoid Cells EGFP+ . | % Colonies G418R . |
|---|---|---|---|---|---|---|
| 5.2.8 | 103-150 | 2 | 0 | NA | NA | 0 |
| 17.2.1 | 18 | 57 | 0 | NA | NA | 0 |
| 17.2.2 | 18 | 72 | ND | ND | ND | ND |
| 18.2.1 | 38 | 38 | 2 | 2 | 2 | ND |
| 18.2.2 | 38 | 37 | 18 | 17 | 17 | 3 |
| 18.2.3 | 38 | 48 | 4 | 7 | 3 | 6 |
| 24.2.1 | 13-150 | 3 | 5 | 2 | 7 | 0 |
| 24.2.2 | 13-150 | 2 | 0 | NA | NA | 0 |
| 24.2.4 | 83-150 | 4 | 0 | NA | NA | 0 |
| 29.2.1 | 53-150 | 54 | 59 | 2 | 1 | 2 |
| 29.2.2 | 53-150 | 13 | 50 | 41 | 52 | 37 |
| 29.2.3 | 53-150 | 7 | 39 | 43 | 39 | 33 |
| 29.2.4 | 53-150 | 31 | 18 | 13 | 15 | 13 |
| 29.2.5 | 18 | 69 | 3 | 5 | 2 | 3 |
| 29.2.6 | 18 | 52 | 12 | 10 | 12 | 8 |
| 30.2.1 | 103-150 | 35 | 4 | 17 | 2 | 11 |
| 32.2.4 | 15 | 2 | 1 | ND | ND | 5 |
| Mouse . | Cells Injected (×105) . | % Human Cells . | % Human Cells EGFP+ . | % Human Myeloid Cells EGFP+ . | % Human Lymphoid Cells EGFP+ . | % Colonies G418R . |
|---|---|---|---|---|---|---|
| 5.2.8 | 103-150 | 2 | 0 | NA | NA | 0 |
| 17.2.1 | 18 | 57 | 0 | NA | NA | 0 |
| 17.2.2 | 18 | 72 | ND | ND | ND | ND |
| 18.2.1 | 38 | 38 | 2 | 2 | 2 | ND |
| 18.2.2 | 38 | 37 | 18 | 17 | 17 | 3 |
| 18.2.3 | 38 | 48 | 4 | 7 | 3 | 6 |
| 24.2.1 | 13-150 | 3 | 5 | 2 | 7 | 0 |
| 24.2.2 | 13-150 | 2 | 0 | NA | NA | 0 |
| 24.2.4 | 83-150 | 4 | 0 | NA | NA | 0 |
| 29.2.1 | 53-150 | 54 | 59 | 2 | 1 | 2 |
| 29.2.2 | 53-150 | 13 | 50 | 41 | 52 | 37 |
| 29.2.3 | 53-150 | 7 | 39 | 43 | 39 | 33 |
| 29.2.4 | 53-150 | 31 | 18 | 13 | 15 | 13 |
| 29.2.5 | 18 | 69 | 3 | 5 | 2 | 3 |
| 29.2.6 | 18 | 52 | 12 | 10 | 12 | 8 |
| 30.2.1 | 103-150 | 35 | 4 | 17 | 2 | 11 |
| 32.2.4 | 15 | 2 | 1 | ND | ND | 5 |
NA indicates not applicable; ND, not done.
These mice received a limiting dose of postculture cells (≤8.8 × 105).